Day 6 Flashcards

1
Q

An ultrafiltrate of blood that fills the spaces within and around the central nervous system

A

Cerebrospinal fluid

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2
Q

3 connective tissues that make up the meninges

A

Dura mater
Arachnoid
Pin mates

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3
Q

Where is CSF formed

A

Found in plexuses which are thin walled capillaries

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4
Q

CSF has more ______,_______,_______ but less _______ than plasma

A

Sodium hydrogen & chloride

Protein

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5
Q

How much CSF Is formed daily?

A

500 ml every 8 hours

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6
Q

3 major functions of CSF

A

Supply nutrients to the nervous tissue
Remove metabolic waste
Cushion the brain and spinal cord against trauma

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7
Q

Where on the spinal column is CSF collected from?

A

In between the 3rd & 4th or 4th & 5th vertebrae

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8
Q

Where does each CSF tube tested

A

Tube 1: chemical and serology testing
Tube 2: microbiology
Tube 3: hematology

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9
Q

What is the most frequently performed chemical test on CSF

A

CSF protein

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10
Q

Csf protein blues are higher in what indivi

A

Infants and older folk

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11
Q

What is the most common cause of elevated CSF protein

A

Meningitis & hemorrhage

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12
Q

What test is performed to fraction CSF protein

A

Electrophoresis

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13
Q

The recommended support medium for electrophoresis is ______ followed by staining with _______

A

Agarose gel

Coomaise blue

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14
Q

Characteristics oligolonal bands observed in the gamma region of a CSF protein electrophoresis indicates what disease?

A

Multiple sclerosis

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15
Q

Norma CSF is what percent of the plasma glucose level

A

60-80%

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16
Q

When should a CSF for glucose be collected

A

2 hours before collecting CSF

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17
Q

Why should samples for glucose CSF be collected immediately

A

Glycolysis occurs rapidly in CSF

18
Q

5 microbiology test that give preliminary diagnosis

A
Gram stain 
AFB stain 
India ink stain 
Counter immunoelectrophoresis 
Latex agglutination
19
Q

A CSF sample for gram stain analysis should be centrifuges at

A

1500 RPM at 15 minutes

20
Q

What is the most common cause of false positive reactions on CSF late text agglutination test

A

Interference of rheumatoid factor‘s

21
Q

How soon should a CSF cell count occur after collection ?why?

A

30 minutes to prevent RBC and WBC from Lysing

22
Q

When is CSF WBC morphology performed

A

Counts > 30wbcs/uL

23
Q

A high CSF WBC with a high percentage neutrophils neutrophils is indicative of what disease

A

Bacterial meningitis

24
Q

An elevated CSF WBC count with a high percentage of lymphocytes and monocytes suggest what disease

A

Meningitis from viral fungal or parasitic faction

25
Q

Serological CSS examination is typically associated with diagnosis of what disease

A

Tertiary or neurosyphilis

26
Q

Treatment with_________ In early stages of syphilis has greatly reduce the number of neurosyphilis cases

A

Penicillin

27
Q

This fluid is a viscous fluid found in joint cavities

A

Synovial fluid

28
Q

Synovial membrane secrete Mucopolysaccharide containing what

A

hyaluronic acid and a small amount of protein

29
Q

A needle aspiration to collect synovial fluid is referred to as

A

arthro-centesis

30
Q

List synovial fluid tube type for each area to be tested

A

Microbiology sterile heparinized
Hematology EDTA
Chemistry/ serology no anticoagulated tube

31
Q

Inflammatory immuno logical problems associated with synovial fluid include

A

Rheumatoid arthritis and lupus

32
Q

Why shouldn’t acetic acid be use for cell counts

A

It will cause and using clotting and said hypotonic Saline should be used to containing methylene blue

33
Q

What is the two primary crystals found in synovial fluid and the disease is associated with them

A
Monosodium urate (Uric acid) Gout 
Calcium pyrophosphate Dihydrate CPPD Psyedogout
34
Q

Three common chemistry test performed on synovial fluid

A

Glucose total protein uric acid

35
Q

A needle aspiration to collect pleural fluid is referred to as

A

Thoracentesis

36
Q

A needle aspiration to collect pericardial fluid is referred to as

A

Pericardiocentesis

37
Q

I need a laceration to collect peritoneal fluid is referred to as

A

Paracentesis

38
Q

Explain the difference between serous fluid transudate and exudate

A

Translates are caused by a mechanical error

Exudates Are caused by inflammatory process and may indicate infection or malignancy

39
Q

Cell counts on serous fluid are done utilizing a

A

Electronics cell counter

40
Q

What causes the possible milky appearance of plural fluid

A

Presence of Chylous material and pseudo-Chylous material

41
Q

What chemistry test can differentiate between serous fluid exudates and transudates

A

Protein
Protein <3g/dL transudates
>3g/dL exudates