Dairy Heifers & Growth Flashcards
Describe colostrum.
-1st milk secreted at time of parturition
-diff from milk secreted later
-contains more lactalbumin & lactoprotein
>rich in ABs = passive immunity to newborn
Describe the nutritional components of colostrum.
- Immunoglobulin
-IgG, IgA, IgM
-85%-90% & 5-7% respectively of total Lg in colostrum with IgGI accounting for 80-90% of total IgG
-IgE present = early protection against intestinal parasites - Maternal leukocytes
-1x10^6 cells/mL of maternal leukocytes, macrophages, T+B lymphocytes, neutrophils - Nutrients
-x4 inc in protein Vs milk
-certain vit & minerals are also inc in Vs milk
Describe the cytokines & GF of colostrum.
-lactoferrin, lactoperoxidase, lysozyme, antimicrobial
-oligosaccharide competitive inhibitor for binding sites on epi surface of intestine
-IGF-I key regulator in development of GIT
-trypsin inhibitor = protect IgG & other proteins from proteolytic degradation in intestine
-TGF-b2 & growth hormone
Describe the imp of passive transfer in calves.
- Inc morbidity & mortality rate
- Dec avg daily weight gain
- Dec milk prod in 1st lactation
- Inc risk of culling in first lactation
Describe the types of placentation.
6 layers
#2
Describe the failure of transfer of passive immunity.
-calf serum IgG conc <10mg/ml * when sampled between 24-48 hrs old
Describe factors affecting adequate passive transfer.
- Timing
>after 24h no passive transfer - IgG conc
- Parity
>more calves = better colostrum - Breed
- Colostrum handling
- Pooling ?
Describe the components of a successful colostrum management program.
- Quality: >50g/L *
-colostrometer, refractometer, cow side immunoassay test
-milk cow ASAP to max IgG conc
-short or no dry period will dec IgG
-vaccinate dam 3-6wk pre calves
-season/vol - Quantity
-4L total for dairy
-rec to feed 10-12% body weight in first feeding
-aim for 100g IgG in first feeding (200 IgG total) - Timing
-first feeding in 1-2h of birth within 6h (latest)
-gut closes at 24h - Method of feeding
-hand feeding w bottle VS esophageal feeder - Handling
-fresh colostrum <100,000 Cfu/ml total bacteria & <10,000 cfu/ml coliforms
-prep udders prior to milking, sanitize collection equipment - bucket, teats, bottle etc
Describe storage & pasteurization.
-refrigerate/freeze within 1h of collection
-keep for 1y when frozen w/o multiple freeze/thaw cycles
-defrost slowly & avoid extreme temp 60c
-duration of refrigeration:
>IgG in raw refrigerated colostrum is stable for 1 week but bacteria counts may reach high conc (bad)
>preserved in K sorbets .5% raw milk last 6d
>pasteurized 8-10d
-normal milk pasteurization unacceptable for colostrum
>milk = 63c for 30 min or 72c for 15s
>colostrum = 60c for 60 min
Describe colostrum replacers & supplements.
-agalactia, supply shortage, death of dam, disease control
-powdered commercial CS or CR products contain bovine Ig-lacteals or plasma derived
-CS: less than 50g of IgG per dose, no nutrient pack, only to supplement (not replace) * existing colostrum [$5-7/dose *]
-CR: min of 100g of IgG per dose, nutritional source of protein, energy, vit, minerals, to completely replace maternal colostrum [$20-30/dose *]
Describe the 3 phases of digestive physiology of the calf.
- Pre ruminant
-2-3wk, negligible dry feed, rely on milk or milk replacer, esophageal groove - Transitional
-until weaning, milk & starter gain, rapid expansion of vol & differentiation of rumen epi so VFA made & absorbed - Ruminant
-at weaning, fermentation of dietary carb to make VFA for most of energy & AA from proteins in the microbial mass
Describe the digestive physiology of the calf & milk.
-milk diet = caesin protein denatured in acidic abomasum (pH2) -> renin + Ca loss -> coagulation of casein protein where fat * is also entrapped in ‘coagulum’ *
>liquid portion: whey, protein, lactose, sol min & vit
—enter SI in 2-3h after meal, casein coagulum = slower
-lactose hydrolyzed -> sugar, glu, galactose, by lactase & monosaccharides absorbed into epi cells by active transport proteins
-pancreatic secretion of amylase + intestinal activity of maltase low at birth then inc over 1st weeks
Describe the digestive physiology of the calf & VFAs.
-calf begin to consume starter conc -> microbial pop ferment carb to VFA (main energy source for ruminants)
-VFA: acetic acid (50-60%), butyric acid (18-20%), propanoic acid (12-18%) *
-butyric acid (lesser extent, proponic acid), stim differentiation of ruminal absorptive epi into papillae
-vol & musculature develop in resp to physical bulk in rumen
-papillae become functional & able to absorb VFA -> pH of rumen stabilizes and begin to inc
-until pH is stable at 6 the ability for cellulolytic bacteria to thrive is limited
Describe nutrient requirements - energy & protein.
-calves <100kg: metabolizable energy (ME) = total feed intake - loss of energy in feces, digestive gasses, urine
-ME requirements for maintenance * under thermoneutral conditions 1.75Mcal/d for 45kg calf = 2.5L of whole milk or 3L milk replacer (lower fat content) *
>thermoneutral: calves <21d is 15-25c & older the lower critical temp is 5c
—bedding: straw best when cold, sand best when hot
-protein req for maintenance + growth as source of AA
-energy = protein req for maintenance small & not altered by temp stress
*EX: 45kg calf req 72.5 g/d of milk replacer powder to meet maintenance req & maintain body temp compared w 382g/d powder under thermoneutral conditions
Describe cold weather feeding strategies.
- Inc vol of milk
- Introduce a 3rd feeding
- Switch to higher energy (higher fat) milk replacer
- Supplement milk replacer w added fat or additional milk solids
- Add additional milk replacer solids to each feeding