D4. Muscles Flashcards

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1
Q

Smooth Muscle

A
  • Long and tapered at each end
  • Only one nucleus
  • Lines the internal organs
  • Involuntary
  • Slower to contract than skeletal
  • Sustain prolonged contractions
  • Does not fatigue easily
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2
Q

Cardiac (heart) muscle

A
  • Forms the walls of the heart
  • Tubular and striated (bands of light and dark)
  • Cells have one nucleus
  • Branched, creating a net-like structure
  • Involuntary
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3
Q

Skeletal (striated) muscle: Function

A
  • Allow body to move
  • Atached to the bone with tendons
  • Protects internal organs
  • Stabilize joints
  • Supports body
  • Helps maintain a constant body temperature
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4
Q

Skeletal (striated) muscle: Structure

A
  • Very long
  • Many nuclei
  • Voluntary - it’s contraction is consciously controlled by the nervous system
  • Striated/tubular
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5
Q

Hierarchy of Muscle Structure

A
  1. Muscle
  2. Muscle-fibre bundle
  3. Muscle fibre
  4. Myofibrils
  5. Myofilaments
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6
Q

Two types of myofilaments

A
  • Actin: Light, thin filaments
  • Myosin: Dark, thick filaments
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7
Q

Sliding Filament Model

A
  • Muscles contract when coordinated sliding and pulling motions occur between Z bands
  • When a muscle is relaxed, myosin heads are not bound to actin
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8
Q

Sacromere

A
  • Section of a myofibril from one Z-line to the next
  • The arrangement of these sacromeres next to each other produces the striations of the skeletal muscle fibers
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9
Q

The Sliding Filament Model

A
  • Muscles contract when coordinated sliding and pulling motions occur between Z bands
  • When a muscle is relaxed, myosin heads are not bound to actin
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10
Q

The Role of Calcium and Regulatory Proteins

A
  • An increase in Ca2+ levels trigger changes that expose binding sites for myosin
  • The myosin heads bind to actin filaments
  • Once bound, the myosin heads will tilt towards the sacromere’s center, sliding the bound actin filament with them
  • The myosin head contains ATPase
  • When ATP binds to a myosin head, the head releases its grip on actin
  • The ATP is hydrolyzed to ADP and the myosin head reverts to its original position
  • If Ca2+ and ATP are still present, the procecss may be repeated
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11
Q

Energy Sources for Contraction

A
  1. ATP reserves: Small amount found around myofilbrils/can provide only a brief contraction
  2. Creatine Phosphate: Initial source of energy to regenerate ATP from ADP and P; only lasts about 10 seconds
  3. Cellular Respiration: Produces up to 38 ATP per glucose molecule (requires O2)
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12
Q

Types of Skeletal Muscle Fibers

Slow-Twitch

A
  • Sustain long contractions, often found in muscles that maintain posture
  • Rely on aerobic respiration
  • Break down ATP slowly, but efficiently to release energy
  • Found in greater abundance in distance runners
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12
Q

Types of Skeletal Muscle Fibers

Fast-Twitch

A
  • Brief, rapid, powerful contractions
  • Rely on glycolysis (anaerobic respiration)
  • Found in abundance in sprinters
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13
Q

Muscle Fatigue

A
  • The inability of the muscles to contract
  • Causes:
  • Lack of oxygen
  • Lack of ATP
  • Accumulation of wastes (lactic acid, pyruvic acid, etc.) → lowered pH is caused by acids, results in increased heart rate
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14
Q

Nerve Control of Muscle Tension

Muscle Twitch

A
  • Skeletal muscles are stimulated by nerves
  • The arrival of nerve impulse causes a muscle fibre to undergo a single contraction or a twitch
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15
Q

Nerve Control of Muscle Tension

Muscle Tonus

A
  • A slightly sustained contraction whereby a muscle is ready for any activity (posture tonus)
16
Q

Nerve Control of Muscle Tension

Summation

A

If a muscle fiber is restimulated before it has completely relaxed, the second twitch is added on to the first, resulting in summation

17
Q

Nerve Control of Muscle Tension

Tetanus

A

A sustained contraction of a muscle (continous muscle contraction b/c of activity)

18
Q

Hypertrophy

A
  • Growth and increase in the size of muscle cells
  • Achieved through specific exercises
19
Q

Muscle atrophy

A

Muscle gets weaker, smaller caused by dormancy

20
Q

Muscular Dystrophy

A
  • Can’t use muscle (paralyzed)
  • Caused by genetic disorders
21
Q

Antagonistic Muscles

A
  • Skeletal muscles that work in pairs and oppose each other