D. 2) Lymphoid Organs Flashcards
primary lmyphoid organs
bone marrow and thymus. hematopoiesis produces lymphocytes that must mature in a primary lmyphoid organ to become immunocompetent
B cells mature in the
bone marrow
T cells mature in
leave the bone marrow and mature in the thymus
secondary lymphoid organs include
lymph nodes, spleen, and mucosa-associated lymphoid tissue (MALT)
MALT includes
Peyers’s patches, tonsils and appendix
fn of MALT organs
to trap antigen. these organs have lots of B and T cells that can produce an adaptive immune response to eliminate the anitigen
the lymph nodes trap antigens from the ___ and the spleen traps antigens from the ____
lymph and blood
where does MALT encounter antigens
on mucosal surfaces in the lungs, digestive tract and urogenital systems
location and structure microfold or M cells
in the digestive tract, Peyer’s patches include epithelial cells called microfold. M cells do not have microvilli. the other side has a large pocket filled with B and T cells, dendritic cells and macrophages
fn of M cells (transcytosis)
take up antigen from the intestinal lumen by endocytosis and then release it into the pocket. the immune cells will have an adaptive immune response to the anitigen