A. 4) Protein Terminology

Question 1

primary structure

Answer 1

sequence of aa of polypeptide. this order is encoded in the gene

Question 2

secondary stucture

Answer 2

refers to localized folding eg alpha and beta sheets

Question 3

tertiary structure

Answer 3

refers to completef olding of one polypeptide

Question 4

Quaternary strucuture

Answer 4

refers to proteins that are formed from more than one polypeptide. each polypeptide is a subunit, may be held together by disulphide bonds

Question 5

protein domain

Answer 5

a part of the protein that has its own tertiary structure and is covalently bonded to the rest of the protein

Question 6

protein family (not to be defined)

Answer 6

proteins that are evolutionary related. although these proteins no longer have primary structure, they retain secondary and tertiary strucuture

Question 7

Ig superfamily

Answer 7

evolved from a gene encoding a single domain. gene was duplicated and even multiple copies combined to encode proteins w/multiple domains. the genes encoding the member of the Ig superfamily then evolved independently resulting in proteins with diff fns