Cytoskelton Flashcards
Which component of the cytoskeleton is responsible for the contractile ring during mitosis
Actin filaments
__________ are transmembrane proteins that mediate cell to cell adhesion
Cadherins
_________ facilitate cell-ECM adhesion
Integrins
Microtubules are made up of what subunit
Tubulin
The cloud which surrounds the centrioles is called
Pericentriolar cloud
The microtubules start at _________ which is a component of paracenteriolar cloud
gamma-tubulin ring
complex
_________ are a family of transmembrane proteins that are known for attaching itself to non-cellular surroundings
Integrins
Where are actin filaments located
Under the membrane
Which actin binding protein is associated with muscle contractions
Myosin
Which filament network are microvilli associated with
Actin filaments
What are the two types of intermediate filaments
Cytoplasmic and nuclear
What are 3 cytoplasmic intermediate filaments
Keratins
Vimentin
Neurofilaments
_________ form a structural framework inside the nuclear envelope
Nuclear lamina
Cilia and flagella are formed by
Microtubules
Which end of the Microtubules are capped?
(-) end
Tubulin heterodimers are added to the growing Microtubule when_________and fall offs when_________
They are GTP bound; when they are GDP bound
2 types of microtubule motor proteins
Kinesin
Dynein
______moves cargo towards the + end
Kinesin
________ moves cargo towards the (-) end
Dynein
Cilia and flagella are both nucleated by one of the following:
A. Centrosomes
B. Basal bodies
B. basal bodies
________causes cilia to move/slide and the protein_____ brings the cilium back to its straight position
ATP hydrolysis: nexin
How many tubules does it take for a cilium to move?
What does each tubule contain?
2
A Dynein and ATPase
The mitosis spindle during mitosis is formed by_______
Microtubules
During the microtubule formation of the mitotic spindle, the (-) ends attach to the _______ and the (+) ends attach to the_______
centrosomes; Kinetochore
Colchine prevents swelling by inhibiting______by binding Tubulin subunits of white blood cells to prevent it from_____to the infected area
Microtubule function; crawling