Cytoplasmic Receptors And Steroid Hormone

Question 1

Outline steroid hormone action;

Answer 1

Steroid hormone pass through plasma memebrane and initiate their actions by binding to cytoplasmic receptors

Question 2

Where do steioid hormones rented and bind ?

Answer 2

Enter through cell membrane and bind to receptors inside of the target cell

Question 3

Steps included in steroid hormone action;

Answer 3

1) entry of hormone into the cell

2) binding of hormone to specific cytoplasmic receptor

3) transfer of hormone-receptor complex to nucleus

4) binding of hormone-receptor complex to genome

5) increase in mRNA levels for specific proteins

6) new proteins- altered cellular function

Question 4

Where is the ligand-receptor complex carried into?

Answer 4

Through the plasma membrane into the cytoplasm of the cell

Question 5

What are symptoms of Graves’ disease?

Answer 5

• enlarged Thyroid gland
• protraction of eyeballs
• rapid heartbeat
• nervous excitability

Question 6

Where are carbohydrates stored?

Answer 6

In liver and muscle cells

Question 7

What is the role of glucagon?

Answer 7

Stimulates the synthesis of glucose from glycerol and amino acids

Question 8

What is Job of human erythrocytes?

Answer 8

Use glucose as metabolic fuel

Question 9

What’s the job of NADH?

Answer 9

• keeps glutathione reduced
• protects cell membrane from oxidation

Question 10

What are the 3 irreversible reactions of glycolysis?

Answer 10

1) glucose+ATP ————> glucose-6-phosphate+ADP

2) fructose-6-phosphate+ATP——-> phosphocructase 1, 6-bisphosphate + ADP

3) phosphornolpyruvage + ADP——> pyruvate + ATP

Question 11

Where is pyruvate carboxylase located?

Answer 11

Located in mitochondria

Pyruvate in Cytosol enters mitochondria