Cytology Flashcards
What is cytology?
- Study of cells
What is histology?
- Study of tissues
What does cytology look for?
- Abnormal cells
- Inflammation/infection
List cytology samples that are fluids
- Haematology
- Urine Sediment
- Body cavity fluids (thoracentesis/pericardiocentesis/adbdominocentesis)
- Tap (joint/CSF)
- Wash (bronchus/prostate)
List cytology samples that are not fluid
- Swab
- Scrape
- Impression smear
- Endoscope brush
- Fine needle aspirate (FNA)
How are cytology fluids analysed?
- Microscopy
- Refractometer
- Biochemistry
- Urine dipstick
- Haematology and PCV
- Culture and sensitivity
How are effusion samples evaluated?
- Appearance
- Total protein
- Total nucleated cell count
- Cytology
- Biochemistry
How are effusions classified?
- Total protein
- Total nucleated cell count
What should be done if classified as total protein?
- Refractometer
- Urine test strips
- Biochemistry for albumin and globulin concentration
What should be done if classified as total nucleated cell count?
- Haematology
- Haemocytometer
What are the causes of effusion?
- Leak from viscus e.g., bladder, gall bladder or gut
- Torn blood or lymph vessel
- Leakage from intact blood vessels
Describe the effusion from the urinary tract
- Torn viscus
- Low TNCC
- Low TP
- High creatinine
- Pale yellow
- Clear turbidity
Describe the effusion from the biliary tract
- Torn viscus
- Low TNCC
- Low TP
- High bilirubin
- Yellow/green
- Clear turbidity
Describe the effusion from the digestive tract
- Torn viscus
- High TNCC
- High TP
- May see gut contents
- Yellow or brown
- Turbid, floccular
Describe the effusion from blood
- Torn vessel
- High TNCC
- High TP
- Many RBC
- Red or brown
- Turbid
Describe the effusion from the lymph
- Torn vessel
- High TNCC
- High TP
- Much fat and lymphocytes
- White or pink
- Turbid
Describe the effusion from low protein transudate
- Leaky vessel
- Low TNCC
- Low TP
- Pale or colourless
- Clear turbidity
Describe the effusion from high protein transudate
- Leaky vessel
- Low TNCC
- High TP
- Yellow
- Clear turbidity
Describe the effusion from exudate
- Leaky vessel
- Low TNCC
- High TP
- Yellow
- Turbid