Cyst management Flashcards
Define cyst
A pathological cavity that is epithelial lined filled with fluid, semi fluid or gas
What will a cyst never be filled with
Pus
How do we classify cysts
Odontogenic
Non odontogenic
What are odontogenic cyst split into
Inflammatory
Developmental
Give examples of inflammatory odontogenic cysts
Radicular
residual
Give examples,es of developmental cysts
Dentigerous
Eruption
Odontogenic keratocyst
Gingival cyst
Developmental
lateral periodontal
How do we classify non odontogenic cyst
- Fissure
- Bone
- Soft tissue
Give examples of developmental non odontogenic cysts
Nasopalatine
Nasolabial
Median palatine
Give examples of non odontogenic bone cyst
Solitary bone cyst
Aneurysmal bone cyst
Give examples of non odontogenic soft tissue cyst
mucous extravasation
Mucous retention
Name the most common cysts
Radicular (65%)
Dentigerous (20%)
Odontogenic Keratocyst (5%)
Where are the originator cells of an inflammatory cyst found
Remnants of henrtwigs roots sheath called cell rests of malassez found in the periodontal ligament
Where are the originator cells of a dentigerous cyst found
Reduced enamel epithelial
Where are the originator cells of an Odontogenic Keratocyst cyst found
dental lamina called glands of serres
Where are the originator cells of an nasopalatine cyst found
Nasopalatine duct epithelium
Where are the originator cells of an mucous retention cyst found
Salivary duct epithelium
Talk through the pathogenisis of cyst formation
- Site specific Inflammation
- Inflammatory cells secrete cytokines such as IL-1 IL-6 TNF and growth factors
State a genetic condition linked to increased cyst development
Gorlin Goltz syndrome
What is Gorlin Goltz syndrome linked with
Genetic defects in the tumour suppressor gene leadign to multiple odontogenic keratocyst
Name the mechanism that describes how cysts get bigger
Hydrostatic mechanism
Talk through the hydrostatic mechanism
- Protein accumulates within the cyst and the wall acts as a semi permeable membrane
- Fluid accumulates in cyst lumen creating positive pressure in the cyst
How can the enlargement of cysts lead to bone resorption
Pro inflammatory cytokines IL1, TNF and PGE2 (Fibroblasts) induce bone resorption
these are produced by cysts stimulation bone resorption
Briefly talk through the mechanism of cyst enlargement
- Inflammation
- Cell proliferation
- Increased protein content
- Fluid accumulates within cyst
- Increased positive pressure
- Displacement of soft tissue
- Resorption of bone
- Cyst increases in size to fill available space
What is the aetiology of radicular cyst
Inflammation
Were are radicular cysts most commonly found
Everywhere but commonest site in maxillary incisors
Describe the presentation of a radical cyst
- Related to a non vital tooth
- Develop within periapical granuloma
- Limited buccal expansion
Describe the radiographic appearance of a radicular cyst
Unilocular well defined well corticated radiolucency at apex of non vital tooth
What is the tx for a radicular cyst
Endodontic tx of non vital tooth
XLA of non vital tooth
What complications can arise form a radicular cyst
Can form a residual cyst following XLA
What is the aetiology of residual cysts
Develops after incomplete removal of a radicular cyst
Where are residual cysts most commonly found
at sites of dental XLA
Describe the radiographic appearance of a residual cyst
Well defined unilocular corticated radiolucency
What is the tx for a residual cyst
Surgical enucleation
What is enucleation
Removal of the cyst epithelium
What is the aetiology of dentigerous cysts
Developmental with an unerupted tooth