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RUVM Pharmacology > CV2 > Flashcards

CV2 Flashcards

1
Q

Class 1A

A

Na Channel Blocker

Prolonged Action potential

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2
Q

Class 1B

A

Na Channel Blocker

Shortened Action potental

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3
Q

Class 2

A

Beta blocker

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4
Q

Class 3

A

K Channel Blockers

Prolongs refractory period without decreasing conductory velocity

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5
Q

Class 4

A

Ca channel blockers

Blocks entry of Ca

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6
Q

What are the Class 1A drugs

A

Quinidine

Procainamide

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7
Q

What are the class 1B drugs

A

Lidocaine

Mexilitine

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8
Q

What are the class 2 drugs

A 
Beta blockers
Esomol
Atenolol
Propranolol
Metaprolol
Carvedilol
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9
Q

What are the class 3 drugs

A

K channel blockers
Sotalol
Amiodarone

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10
Q

What are the class 4 drugs

A

Diltiazen

Magnesium Sulfate IV

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11
Q

Ventricular drugs

A 
Quinn Eats Anna's Pretty Donuts Daily
Quineline
Esmolol
Atenolol
Propranolol 
Diltiazem
Digoxin
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12
Q

Supreventricular drugs

A 
Peggy Licks Megans Stolen Apple Meusem
Procainamide
Lidocaine
Mexilitine
Sotalol
Amiodarone
Magnesium Sulfate IV
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13
Q

DOC for supraventicular arrythmyias in horses

A

Quinidine

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14
Q

DOC for supraventrical arrythmias

A

Diltiazem

Quinn eats anna DONUTS daily

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15
Q

DOC for ventricular

A

Lidiocaine

Peggy LICKS megans stolen apple meusum

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16
Q

Quinidine

A

Class 1A Na channel blocker
Prolong action potential
DOC for supra in horses

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17
Q

Procainamide

A 
class 1A Na blocker
Prolong AP
Ventricular
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18
Q

Lidocaine

A

Class 1B Na
SHortens AP
DOC for venticular

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19
Q

Mexilitine

A

CLass 1B Na
Shorten AP
ventricular

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20
Q

What are Class 2 non selective

A

esmolol
atenolol
metaprolol

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21
Q

MOA of CLass 2

A

Beta blockers

Inhibit effects of catecholamines on heart

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22
Q

If your putting a patient on CLass 2…what do they need

A

a stable heart

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23
Q

Propranolol

A

Class 2 beta blocker
non selective beta antagonist
supraventricular —pretty
Quinn eats anna pretty donuts daily

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24
Q

Esmolol

A

Class 2 beta blockers
Selective beta 1
Supraventricualr
ultra short acting

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25
Q

Atenolol

A

Class 2 beta blocker
Selective beta 1
Supraventricular

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26
Q

Metaprolol

A

Class 2 beta blocker

Selective bera 1 antagonist

27
Q

Carvedilol

A

Class 2 beta blocker
non selective beta antagonist
selective alpha 1 antagonist

28
Q

What are the class 3

A

Sotalol

Amiodarone

29
Q

Both class 3 drugs treat

A

ventricular
Peggy licked megans STOLEN APPLE meusem
Sotalol
Amiodarone

30
Q

Sotalol

A

Class 3 K blocker
non selective beta blocker
Ventricular
Peggy licked megans STOLEN apple meusum

31
Q

Amiodarone

A

Class 3 K blocker
Ventricualr
Peggy licked megans stolen APPLE meusum viruoisly

32
Q

What are the class 4 drugs

A

Diltiazem

Mg Sulfate IV

33
Q

Which class 4 drug tx ventricular arrthymias

A

vnszium Sulfate IV

34
Q

What class 4 drug treats supraventricular

A

Diltiazem

DOC

35
Q

Diltiazem

A

Class 4 Ca channel blocker
DOC supraventricular
Oral may be toxic

36
Q

Magnesium Sulfate IV

A

Class 4 ca channel blocker

Tx refractory ventricular arrhythmias

37
Q

What do ACE inhibitors inhibit?

A

Inhibit angiotensin coverting enzyme
Inhibit angiotension 2 synthesis
Inhbit aldosterone
Increase vasodilator

38
Q

What is the goal of an ACE inhibitor

A

Vasodilate

39
Q

Enalapril is a what?

A

ACE inhibitor

40
Q

Benazepril

A

ACE inhibitor

Longer acting than Enalapril

41
Q

Goal of Phosphodiesterase Inhibitor?

A

Nitrooxide mediated vasolation

42
Q

What drug is a phosphodiesterase innhibitor that vasodilates?

A

Sidenafil

43
Q

What is the DOC for pulmonary hypertension?

A

Sidenafil

44
Q

Nitrates are contraindicated with what vasodilator

A

Sidenafil

45
Q

Sidenafil MOA

A

phosphodiaesterase innhibitor

NO mediated vasodilation

46
Q

Sidenafil

A

Phosphodiesterase inhibitor
NO mediated vasodilation
DOC pulmonary hypertension
Contraindicated with concurrent nitrates

47
Q

What are the direct acting vasodialtors

A

Nitrates

Hydralazine

48
Q

What are the direct acting vasodilating nitrates?

A

Nitroprusside

Nitroglycerine

49
Q

MOA of Nitrates

A

Increased NO formation

direct acting arteriole & venous vasosilation

50
Q

What drug directly vasodilates BOTH arterioles & venous

A

Nitrates

Nitroprusside & Nitroglycerine

51
Q

What drug directly vasodilates arterioles?

A

Hydralazine

52
Q

MOA of Hydralazine

A

Increased local PGI2 cocentration

Directly vasodilates arterioles

53
Q

What do you use to treat a true hypertension crisis?

A

Direct acting vasodilators

Nitrates & hydralazine

54
Q

Hydralazine is contraindicated with what disease

A

renal disease … for once its not cats holy fuck

55
Q

Role of Ca channel blockers regarding vasodilation

A

Reduce systemic blood pressure

56
Q

How to Ca channel blockers reduce systemic blood pressure

A

decrease peripheral resistance

decrease afterload

57
Q

What are the Ca Channel blocker vasodialtors

A

Amlodipine

58
Q

MOA o Amlodipine

A

inhibits influx of extracellular Ca –> dilation of coronary & systemic arteries

59
Q

Amlodipine is the DOC for??

A

Hypertension in Cats!! meowwwwww

60
Q

What do angiotension 2 antagonist do?

A

vasodilate!

61
Q

What are the angiotension 2 antagosit vasodilators

A

Losartan

62
Q

MOA of Losartan

A

Angiotension 2 receptor competitive antagonist

63
Q

What is Losartan used to treat?

A

Anti-hypertensive adjucant therapy

so i guess nothing just like prevention

RUVM Pharmacology (5 decks)

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