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Cardiovascular > CV Tumors > Flashcards

CV Tumors Flashcards

1
Q

Most Heart tumors are…?

A

Metastases, not primary; lung, melanoma, breast, leukemia, lymphoma

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2
Q

What are the most primary heart neoplasms

A

Myxoma

Rhabdomyoma

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3
Q

What is the histology of myxoma

A

Myxoma cells embedded in abundant ground substance

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4
Q

What is carney syndrome

A

AD or AR disorder

Multiple myxomas - skin, heart, breast, etc

Spotty pigemntation

Endocrine overactivity

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5
Q

What is rhabdomyoma associated with

A

Tuberous sclerosis

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6
Q

What is the histology of rhabdomyoma

A

spider cells - myocytes w/ vacuolations

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7
Q

Multiple firm, white nodules

A

Rhabdomyoma gross appearance

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8
Q

Other primary heart neoplasms

A

Lipomas - asymptomatic; ball-valve effect

Papillary fibroelastmas - on valves; can emobilize

Angiosarcomas

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9
Q

What are the benign vascular neoplasms

A

Hemangioma
Glomus tumor
lymphangioma
bacillary angiomatosis

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10
Q

What are the intermediate vascular neoplasms

A

Kaposi’s

Hemangioendothelioma

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11
Q

What are the malignant vascular neoplasms

A

Angiosarcoma

Hemangiopericytoma

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12
Q

Types of hemangiomas

A

Strawberry/juvenile

Cherry/adult

Pyogenic granulomas

Cavernous hemangioma

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13
Q

What are pyogenic granulomas

A

hemangiomas that can bleed r ulcerate; seen w/ pregnancy or trauma

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14
Q

What are cystic hygromas

A

cavernous lymphangiomas; neck/axilla; infants/children; blood vessels devoid of blood

Seen in Turner syndrome

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15
Q

What causes bacillary angiomatosis

A

Bartonella infection - HIF-1 secretion leading to capillary proliferation

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16
Q

Types of Kaposi’s Sarcoma

A

Chronic - classic type; multiple red to purple skin nodules

Lymphadenopathic - African; very aggressive

Transplant - localized or widely metastatic; may not have cutanous lesions

AIDS-associated

17
Q

Which virus is associated w/ Kaposi’s sarcoma

A

HHV-8; found in 95% of lesions

18
Q

Morphology of Kaposi’s

A

spindle cells

19
Q

Treatment of Kaposi

A

Resection/cryotherapy
Radiation
Chemotherapy
If related to immunosuprression; decrease suppression, angiogenesis inhibitors

20
Q

Causes of angiosarcoma

A

Liver - arsenic, polyvinyl chlorid, thorotrast

Post-radial mastectomy

Post radiation

21
Q

Angiosarcoma histology

A

Well differentiated - vascular channels

Less differentiated - spindle cells

22
Q

Angiosarcoma prognosis

A

Poor - 5 year survival is 30%

23
Q

Causes of lymphangiosarcoma

A

Radical mastectomy

Setting of lymphatic obstruction

Cardiovascular (12 decks)

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