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my drugs > CV drugs: angina, MI, thrombosis > Flashcards

CV drugs: angina, MI, thrombosis Flashcards

1
Q

What drugs are used as first-line treatment of stable angina?

A

Beta blockers

Calcium Channel Blockers

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2
Q

Cardio-selective beta blocker used in angina?

A

Atenolol

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3
Q

Mode of action of Atenolol?

A

Reduces HR and force, lowering myocardium’s oxygen requirements.

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4
Q

Side effects of Atenolol?

A

Cold peripheries
Fatigue (reduced skeletal muscle perfusion)
Bradycardia

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5
Q

CCB used in angina?

A

Amlodipine

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6
Q

Mode of action of Amlodipine?

A

Peripheral arteriolar dilatation - reduces afterload.

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7
Q

Side effects of Amlodipine?

A

Ankle oedema

Hypotension and dizziness

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8
Q

What drug is used for symptom relief in angina?

A

Nitrates (GTN spray)

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9
Q

Mode of action of GTN spray?

A

NO mediates vasodilatation:

-Increases perfusion of ischaemic zones of myocardium

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10
Q

Possible problems with GTN use?

A

Repeated use can cause tolerance

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11
Q

Drugs used to treat / prevent arterial thrombosis?

A

Antiplatelet drugs

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12
Q

Antiplatelet drugs used?

A

Aspirin
Clopidogrel
Tricagrelor
Prasugrel

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13
Q

Drugs used to treat / prevent venous thrombosis?

A

Anticoagulants

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14
Q

Anticoagulants used?

A

Warfarin
Low MW Heparin (Dalteparin)
Rivaroxaban
Dabigatran

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15
Q

What is warfarin used for?

A

DVT
PE
AF

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16
Q

Mode of action of Warfarin?

A

Blocks clotting factors 2,7,9 and 10

17
Q

What is Rivaroxaban used for?

A

DVT

PE

18
Q

Mode of action of Rivaroxaban?

A

Clotting factor Xa inhibitor

19
Q

What drugs are used to treat already formed clots?

A

Fibrinolytics

20
Q

Fibrinolytic used in STEMI, PE and stroke?

A

Streptokinase

21
Q

Pharmacological treatment of MI?

A 
MONA-C
Morphine
Oxygen (if <94%)
Nitrate
Aspirin
-Clopidogrel/Tricagrelor/Prasugrel

PCI or Thrombolysis

my drugs (7 decks)

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