CV Flashcards

1
Q

oncotic pressure

A

the pressure pulling fluid back into vessels- caused mainly by albumin and large negatively charged proteins

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2
Q

haemostasis

A

the stoppage of bleeding

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3
Q

intrinsic pathway

A

everything necessary for it is in the blood. necessary for continuation of the coagulation cascade

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4
Q

extrinsic pathway

A

needs a cellular component outside the blood (tissue factor) most important in the initiation of the coagulation cascade

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5
Q

poiselles law

A

flow= 1/radius to the power of 4

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6
Q

Cardiac output

A

CO= HR X Stroke Volume

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7
Q

Blood pressure

A

BP= CO X total peripheral resistance

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8
Q

determinants of total peripheral resistance

A

radius of the vessel which is determined by the contraction of the smooth muscle within the cell

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9
Q

Ohm’s Law

A

Flow= pressure gradient/ resistance

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10
Q

Frank Starlings Law

A

The stroke volume increases as the end diastolic volume increases

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11
Q

reactive hyperemia

A

when an organ or tissues blood flow is occluded the blood flow increases by flow autoregulation and active hyperemia to the organ/ tissue until the occlusion is removed

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12
Q

Active hyperemia

A

a manifestation of increased blood flow to an organ or tissue when its metabolic activity increases

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13
Q

flow autoregulation

A

the control of blood pressure in response to changes

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14
Q

isovolumetric contraction

A

when the ventricles are contracting but all the valves are closed so no blood is ejected

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15
Q

medullary tonic activity

A

an increased tonic activity is increased activity within the organ/tissue.

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16
Q

Describe the 4 forces that affect starlings Law

A

plasma hydrostatic pressure, interstitial hydrostatic pressure, osmotic pressure in the capillary, and osmotic pressure in the interstitial fluid.

17
Q

Sickle Cell anamenia key point

A

autosomal recessive transmission
glutamate is replaces by valine due to a change in base sequence
this mutation is at the recognition site for the cleavage of B-globulin gene
b-globulin gene is not cleaves thus produces a misfolded protein, this affects the stucture of the Haemoglobin and thus the red blood cell. Sickle Shaped!

18
Q

Total peripheral resistance

A

The sum of all the resistance in peripheral vasculature in the systemic circulation

19
Q

Mean arteriole pressure

A

Cardiac output X total peripheral resistance

20
Q

Time interval of the p wave

A

0.1 s

21
Q

Time interval of the PR complex

A

0.12-0.2 s

22
Q

Length of the QRS complex

A

0.06- 0.1s

23
Q

Length of the ST segment

A

0.2s-0.4 s

24
Q

Length of the T wave

A

0.4 s