Cushing's syndrome Flashcards

1
Q

How is cushings treated?

A

Mostly surgery.
Metyrapone has been found to be helpful in controlling the symptoms of the disease, it is also used to prepare patients for surgery.

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2
Q

What kind of dose of metyrapone is used to either control the symptoms of Cushings or prepare a patient for surgery?

A

Either high or low.

If high, corticosteroid replacement therapy is also needed.

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3
Q

Why would ketoconazole be used in patients with Cushing’s disease?

A

It may have an effect on corticotropic tumour cells. It is also used under specialist supervision for the treatment of endogenous Cushing’s syndrome.

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