Csf Flashcards
outermost membrane outermost membrane
dura matter
middle
* Pia mate
Arachnoid mater/Arachoidea “spider-web-like”
innermost layer and
adheres to the surface pf neural tissue.
- Pia mater “gentle mother”
Functionof csf
- Serves as a mechanical barrier against trauma
- Provides supply of nutrient to CNS tissue
- Remove metabolic wastes
CSF is produced via active transport secretion and filtration by the
____ of each of the four ventricles of the brain
choroid plexuses
Rate of production:
0.3 to 0.4 mL/min, ~ 20 mL/hr
volume adults
140 to 170 mL or 90 to 150 mL
neonates volume
10 to 60 mL
Used to represent the control and filtration of blood
components to the CSF and to the brain
Brain-Blood Barrier (BBB
In the choroid plexuses, the endothelial cells have a very tightfitting junctures that prevent the passage of many molecules.
These structures are termed as the
Brain-Blood Barrier (BBB)
- routine method for CSF collection, done
with fetal position or lateral decubitus position
lumbar puncture
sites of lumbar puncture inadults
Between 3rd and 4th (or lower) lumbar vertebrae
site of lumbar puncture in children
Between 4th and 5th lumbar vertebrae
puncture in sub-occipital region (cisterna magna)
Cisternal puncture
puncture for - infants with open fontanels
Ventricular puncture
order of collection: 1st tube test and storage?
Chemical and serological test; frozen at -15 to 30 deg cel
order of collection: 2nd tube
Microbiological test; room temp at 19 to 26deg cel
Order of collection; 3rd tube
cell count; refrigerated at 2 to 8 deg cel
tube 4
microbiology to chemistry or serology
order or collection; low volume csf
micro to hema to chem
order of collection; excess csf
mix together
stat basis
within 30 minutes
Appearance and color
clear and colorless
pH
7.4