CS200- Cells, skin, and cranium Flashcards
Interstitial Space
The space outside the cells and the vascular system
Most abundant cations
K+, Na+, Ca+, Mg+
Most abundant Anions
Cl-, HCO3-, HPO4-
Cytosol
Clear fluid in the cytoplasm
Thrombocyte
Platelet
Cytokine
Protein Produced by WBC’s, instructs neighboring cells to respond in a genetically preprogrammed fashion
Function of the smooth ER
Synthesizes Lipids
Functions of the rough ER
Synthesizes proteins
Function of the Golgi aparatus
Packages and secretes enzymes and mucus
Persoxisomes
abundant in the liver, absorbc and neutralizes toxins
Lysosomes
Contain digestive enzymes that protect against disease
Endocrine Glands
Hypothalamus Pituitary Thyroid Parathyroid Thymus Pancreas Adrenal Gonads Pineal
Body Fluid Compartments
Intracellular- 75%
Extracellular- 25%
Interstitial- 17.5%
Intravascular- 7.5%
Bicarbonate Buffer System
H+ + HCO3- — H2CO3 — CO2 +H2O
Sebacious Glands
Within the dermis, produces sebum and secretes it onto the surface of the skin or onto hair follicles
Sudoriferous Glands
Within the dermis, secrete sweat
Subcutaneous Tissue (Hypodermis)
Tissue underlying the dermis
Rich and fatty, helps absorb impact, conserves body temp
Blood goes over or under to conserve or release body heat
Blood % of body weight
6%
ml blood/kg body weight
80-85
Erythropoietin
Produced mostly in kidneys, stimulates the production of Erythrocytes (RBCs) in bone marrow
Hemoglobin: O2 capacity
1g can carry 1.34ml O2
Homoglobin: affinity decreases as
Temp Rises PO2 lowers PCO2 rises pH decreases Conc of 2,3-DPG (2,3-disphosphoglycerate increases)
RBC Life Span
120 days
hematocrit (and conc)
The packed cell volume of RBC’s per unit blood (generally 40-53%)
3 categories of Leukocytes
Granulocytes, Monocytes, Lymphocytes
chemotaxis
the movement of leukocytes in response to chemical signals
3 Types of mainblasts (and mature forms)
Myeloblasts- Granulocytes
Monoblasts- Monocytes
Lymphoblasts- Lymphocytes
3 types of Granulocytes and their functions
Basophils- basic, blue, store histamine with which to respond to allergic reactions.
Eosinophiles- Acidic, red. Inactivate mediators of acute allergic reaction, controlling anaphalactic response
Neutrophils- pale blue and pink. fight infection via phagocytosis
Monocytes
Category of Leukocytes. collect trash, stimulate granulocyte production
Lymphocytes
Category of Leukocytes. Primary cells involved in immune response. Highly specialized, contain receptors for specific foreign proteins. T cells and B cells
T cells
Category of Lymphocyte (leukocyte). Mature in Thymus gland. Cellular immunity, reject transplants
B cells
Category of Lymphocyte (leukocyte). Humoral Immunity. Produce antibodies to combat infection, originate in bone marrow.