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MSK Revision > Crystal Arthropathy > Flashcards

Crystal Arthropathy Flashcards

1
Q

What are the 2 types of crystal arthropathy?

A

Gout and pseugogout

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2
Q

What crystals form in gout?

A

Monosodium urate

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3
Q

what crystals form in pseudo gout?

A

Calcium pyrophosphate Dehydrate (CPPD)

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4
Q

What infringement does a monosodium urate crystal show on polarised light?

A

Negative

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5
Q

What infringement does a calcium pyrophosphate crystal show on polarised light?

A

POSITIVE

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6
Q

Is gout more common in men or women?

A

Men

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7
Q

What is the peak of incidence?

A

40-60

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8
Q

What is the main cause?

A

HyperURICAEMIA

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9
Q

What things can cause high uric acid?

A 
Alcohol 
High PURINE foods
Dehydration 
Psoriasis 
Diuretics 
Meat
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10
Q

What is the pathology of crystal arthropathy?

A

Purines are a breakdown product of DNA and food, when hyperuricaemia occurs the excess loses an ion in the blood joins to sodium and form a crystal depositing in the joints

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11
Q

What is the levels of HyperURICAEMIA in the blood classified as?

A

over 6.7mg/dL

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12
Q

What are the clinical symptoms of gout?

A 
BIG TOE
Very painful acute 
Red, hot, swelling joint 
wakes up with the toe on fire 
Pyrexia
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13
Q

what is the clinical presentation of pseudogout?

A

The same as gout but in the KNEE or ANKLE!!1

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14
Q

what are you investigations?

A

Aspiration of the joint and microscopy
FBC,WBC
X-ray
Clincial

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15
Q

What is the management of the 1st cute gout attack

A

Nothing, only if recurrent
NSAIDS’s
Colchichine

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16
Q

What is the management of recurring gout?

A

Allupurinol 300-600mg = Xanthine oxidase inhibitor

Colchichine if GI upset

17
Q

What is pseudogout commonly associated with?

A

Chondrocalcinosis - calcification of the cartilage

18
Q

who get pseudogout?

A

Elderly females

MSK Revision (14 decks)

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