Cromoglycic acid derivatives

Question 1

Cromoglycic acid derivatives. Mechanism of action

Answer 1

• stabilize mast cell membranes and inhibit theirdegranulation due to reduced entry of ionized calcium into the cytoplasm
• have a specific anti-bradykinin effect, which leads to the development of a local anti-inflammatory effect

Question 2

Cromoglycic acid derivatives. Indications :

Answer 2

atopic bronchial asthma (prevention of attacks)

allergic rhinoconjunctivitis

Question 3

Cromoglycic acid derivatives. Unwanted side effects :

Answer 3

local irritant effects (cough, burning sensation

Question 4

Mast Cell Membrane Stabilizers. Drugs

Answer 4

Cromoglycic acid

Lodoxamide

Question 5

Mast Cell Membrane Stabilizers

Answer 5

blocking the release of allergy mediators:

• interrupt allergic inflammation,
• reduce permeability,
• warn reflex bronchoconstriction,
• inhibit the immediate reaction of the bronchi to the allergen.