Crohn's and Ulcerative Colitis

Question 1

Which occurs more commonly in children UC or Crohn’s?

Answer 1

Crohn’s

Question 2

Where in the GI tract does UC affect?

Answer 2

Begins at rectum and is continuous along the colon

Question 3

What is the difference histologically between Crohn’s and UC?

Answer 3

Crohns= transmural
UC= epithelial

Question 4

What is the name for UC that only affects the rectal area?

Answer 4

Proctitis

Question 5

Which is Th2 mediated?

Answer 5

UC

Question 6

Which is Th1 mediated?

Answer 6

Crohn’s

Question 7

What is the definitition of severe UC?

Answer 7

More than 6 bloody stools in a day + 1 of:
Fever
Tachycardia
Anaemia
Elevated ESR

Question 8

In which disease is smoking protective?

Answer 8

UC

Question 9

What is the cardinal symptoms of UC?

Answer 9

LIF pain

Question 10

What extra intestinal manifestations can present in IBD?

Answer 10

Clubbing
Apthous oral ulcers
Erythema nodosum
Pyoderma gangrenosum
Angular chelitis
Uevits
Spondylitis
Amyloidosis 
Episcleritis

Question 11

Which disease is often characterised by peri anal disorders?

Answer 11

Crohns

Question 12

Which is granulomatous?

Answer 12

Crohns

Question 13

What is the definition of an extensive colitis?

Answer 13

extends beyond splenic flecture

Question 14

What is the most worrying complication of UC?

Answer 14

Toxic megacolon

Question 15

Which disease of the bile duct is associated with UC?

Answer 15

Primary sclerosing cholangitis

Question 16

What is used to treat UC?

Answer 16

5- aminosalicyclic acid
Steroids
Immunosuppression
Anti alpha TNF therapy

Question 17

Name an example of a 5-ASA

Answer 17

Mesalazine

Question 18

In which disease is surgery not curative?

Answer 18

Crohns

It is curatice in UC

Question 19

Where in the GI tract does crohn’s affect?

Answer 19

Anywhere

Characterised by ‘skip lesions’

Question 20

Where is the most commonly affected site of crohns

Answer 20

The ileocaecal junction

Question 21

What is the ‘classical’ clinical finding in crohns?

Answer 21

Right illiac fossa mass

Question 22

What are the possible complications of crohns?

Answer 22

Malabsorption
Short bowel syndrome - iatrogenic
Gallstones
Strictures/bowel obsturction

Question 23

What is the treatment for crohns?

Answer 23

Stop smoking
Steroids
Immunosuppressants
Anti- tnf

Question 24

What steroids would you give in IBD?

Answer 24

Prednisolone

Budesonide

Question 25

What immunosuppresion therapy woudld you give?

Answer 25

Azathipine
Mercaptepurine
Methotrexate

Question 26

Name an anti TNF therapy.

Answer 26

Infliximab