Cranial Nerves Flashcards
Describe the route of the olfactory nerve (CN 1)
Begin in the route of the nasal cavity → Cribiform foramina (in plate of ethmoid bone) → Olfactory Bulb → Olfactory Tract → Temporal lobe
What is the key function of the olfactory nerve?
Sensory: smell
What is the most common cause of anosmia (loss of sense of smell)?
What other things can cause anosmia?
Most common: Respiratory Tract Infection
Other causes:
- Head injury - shearing force/ basilar skull fracture
- Tumour at base of frontal lobe
Describe the route of the optic nerve
From the retinal ganglion cells → axons form the optic nerve → exits the orbit via the optic canal → fibres cross and merge at optic chiasm
Where in the brain is vision pervieved and which nerve sends these impulses?
Impusles sent by the optic nerve to the primary visual cortex
A tumour in which location can cause bilateral visual symptoms?
Pituitary tumour → causes compression of the optic chiasm
How would you test the optic nerve?
- Visual acuity test (Snellen Chart)
- Visual Fields
- Pupillary light response
Explain what a papillodema is
Papillodema = swollen optic disc
Optic nerve carries extensions of the meninges so can be affected when ICP is raised (tumour/ bleeds)
Describe the route of the Occulomotor nerve (CN 3)
From the midbrain → Lateral wall of cavernous sinus → through superior orbital fissure → to extra ocular muscles
What is the function of the oculomotor nerve (CN3)?
Motor: to most of the muscles moving the eyeball (extra-ocular muscles) and the muscles of the eyelid (Levator Palpebrae Superioris)
Parasympathetic fibres: innervate the sphincter pupillae muscle causing contriction in bright light
Explain why damage to the occulomotor nerve can cause a blown pupil?
- The oculomotor nerve is vulnerable to compression between tentorium cerebelli and the uncus of the temporal lobe when ICP is raised
- Parasympathetic fibres are carried on the outside of the nerve, therefore compression squashes the parasymapthetic fibres
- Parasymapthetic fibres normally cause constriction → THEREFORE constriction allows unapposed dilation and ‘blown’ pupil appearance
A patient presents with this appearance. Which nerve is injured and explain why the eye looks like this
cranial nerve 3 - oculomotor nerve injured or compressed
Severe ptosis: normal function of oculomotor will be to raise the eyelid (levator palpabrae superioris) , a damaged oculomotor nerve will not be able to do this so eyelid droops
Blown pupil: due to compression of parasympathetic fibres → unapposed dilation of pupil
How would you test the function of the oculomotor nerve?
- Inspect eyelids and pupil size
- Test eye movement and pupillary light reflex
- Asses whether patient has double vision
What injuries/ pathology can cause injury to the oculomotor nerve. Which of these is pupil sparing?
- raised ICP from tumour or haemorrhage
- Aneurysm
- Cavernous sinus thrombosis
- Vascular (secondary to diabetes/ hypertension) is pupil sparing
Describe the route of the trochlear nerve
From the midbrain → lateral wall of cavernous sinus → through superior orbital fissure → to 1 muscle of teh eyeball suprior oblique
What is the function of the trochlear nerve (cranial nerve 4)?
Motor: Innervates 1 extra-ocular muscle: Superior oblique (abducts, depresses and internall rotates the eye)
Which of the cranial nerves has the longest intracranial course and why?
Trochlear nerve (CN4)
Has the longest route as it is the only one to originate from the dorsal aspect of the brainstem
How do lesions to the trochlear nerve present?
2 eyes don’t align causing double vision (diplopia)
Often rare and subtle- patients usually correct by tilting the head
Vulnerable to damage in raised ICP due to long route
Describe the route of the Trigeminal nerve (CN 5)
Originates in the pons → branches in the trigeminal ganglion where it splits into 3 branches:
- Va Opthalmic- through superior orbital fissure into the orbit
- Vb Maxillary - through foramen rotundum to pterygopalatine fossa
- Vc Mandibular- through foramen ovale to inframtemporal fossa
What is the function (s) of the Trigeminal Nerve (CN5)?
Sensory: main sensory supply to skin of face and scalp
Sensory to deeper structures within the head (paranasal sinuses), anterior part of tongue and meninges
Motor: to muscles of mastication Vc only
How would you test the function of the trigeminal nerve?
- Check sensation by touching facial dermatomes
- Test muscles of mastication (jaw jerk)
What is trigeminal neuralgia?
A sharp, excutiating pain of the face lasting s → 2 minutes
What is opthalmic shingles and why is this a sight threatening condition?
Shingles in the dermatome of the opthalmic branch of the trigeminal nerve
Sight threatening as scarring of the cornea can cause blindness
What are the branches of the Opthalmic Division of the Trigeminal nerve and what is the function? (Va)
Frontal, Lacrimal, Nasociliary
Main sensory fibres of the eye, conjunctive, orbital contents and structures deep to the dermatome
Frontal branch exits from orbit as supraorbital and supratrochlear to carry senory info from forehead