CPS Adolescent health Flashcards
A family is undergoing family-based treatment with you for their daughter who has an eating disorder. They are struggling to gain her cooperation since they are very busy to enforce refeeding. Furthermore, parents are separated. They also wonder whether they should remove her from school. What are your recommendations?
-for many parents, a leave of absence or reduced hours at work is needed to ensure adequate supervision of nutrition = write them a letter to their employer -continue schooling for the child but if there is concern the child is not eating their lunch, parents may need to bring the child home for lunch -reinforce the need to stop all physical activity as the refeeding process gets started -reinforce to parents that the time commitment and intense supervision required at the beginning of treatment is time well spent and offers the child the best chance of complete recovery -reinforce that the illness has affected the child’s ability to adequately care for themselves and that without the parents being a united front and taking charge, recovery will not occur.
Amenorrhea What are the causes of primary and secondary Amenorrhea?
An adolescent patient comes to you after having unprotected sex. She does not want to take Plan B or Yuzpe and instead requests a copper IUD. -what are the criteria for insertion? -what is your management?
Criteria: should be considered for use up to 7 d after unprotected sexual intercourse for women who are in a stable, mutually monogamous relationship and at low risk for STIs -Management: 1. Exclude existing pregnancy: order pregnancy test 2. At time of insertion, endocervical specimens for chlamydia and gonorrhea 3. CONSIDER prophylactic antibiotics for both chlamydia and gonorrhea ***IUD can be removed during or after the next period
An adolescent patient comes to you because they took Plan B and then vomited 20 minutes later. She asks if she should take it again. What do you say?
Yes she should! If vomiting occurs within 1 hr of taking emergency contraception, should retake the dose.
An adolescent patient has chosen to take emergency contraception after having unprotected intercourse. She asks you when she can start taking her regular OCP again. She also wants to know when she should come back for follow up. What do you say?
-Can start a new pack of pills the day after she takes EC. -book f/u appointment for 1 wk after her next expected menstrual period. At that appt, can counsel about choices regarding sexual activity, contraception, STI and safer sex. -may need a pregnancy test if next period is more than 1 wk late, unusual, heavy bleeding or pain.
Anorexia How do you calculate TGW based on old charts?
Current weight: 39.6 kg. Height: 163 cm
What would her target goal weight be based on
this new information?
Anorexia How do you Calculate TGW based on weight when lost menses?
Current weight: 39.6 kg. Height: 163 cm
Girl remembers she lost her period around 43.2kg but
can’t be sure. Calculate a target goal weight based on this information
- 2 kg + 2 kg = 45.2 kg
- 6 kg / 45.2kg = TGW of 87.6%
Anorexia How do you calculate TGW based on BMI?
You are in ED seeing a 16 year old patient with likely Anorexia
Nervosa. Her current weight: 39.6 kg. Height: 163 cm. Her physical exam is normal and her orthostatic vitals are
also within normal limits. You do not have access to any growth
records. She is with her Dad and he doesn’t remember what weight she was when she lost her period.
Calculate a target goal weight
50%ile BMI for 16 year old female = 20.5 kg/m2
- 5 kg/m2 x 1.63 m x 1.63 m = 54.5kg
- 6kg/54.5 kg = TGW 73%
Anorexia nervosa Wha are the recommended tests in a child with suspected eating disorder?
- CBC and ESR
- Renal, bone bioch, LFT’s and albumin
- Endocrine:
a. TFT’s
b. FSH, LH, Estradiol, Prolactin if ammenorrhea - ECG
- BMD if no preiods for 6 months
Anorexia nervosa What are the clinical features of eyes, teeth, salivary glands, throat, heart cf binge eating/purging
Anorexia nervosa What are the clinical features of GIT, MSK, CNS, mental cf binge eating/purging
Anorexia nervosa What are the clinical features of weight, metabolism, skin and hair cf binge eating/purging
Anorexia nervosa What are the optional tests in a child with suspected eating disorder?
- GIT
a. Upper and small GIT series & Barium enema
b. Celiac screen - Brain MRI to r/o brain tumor
Anorexia nervosa What are the 2 types of anorexia nervosa ?
Restricting type:
During the last 3 months, the individual has not engaged in recurrent episodes of binge eating
or purging behavior (i.e., self-induced vomiting or the misuse of laxatives, diuretics, or enemas). This subtype
describes presentations in which weight loss is accomplished primarily through dieting, fasting, and/or
excessive exercise.
Binge-eating/purging type:
During the last 3 months, the individual has engaged in recurrent episodes of
binge eating or purging behavior (i.e., self-induced vomiting or the misuse of laxatives, diuretics, or enemas).
Anorexia nervosa What is the DSM 5 criteria for anorexia nervosa?
A. Restriction of energy intake relative to requirements, leading to a significantly low body weight in the
context of age, sex, developmental trajectory, and physical health. Significantly low weight is defined as a
weight that is less than minimally normal or, for children and adolescents, less than that minimally expected.
B. Intense fear of gaining weight or of becoming fat, or persistent behavior that interferes with weight gain,
even though at a significantly low weight.
C. Disturbance in the way in which one’s body weight or shape is experienced, undue influence of body weight
or shape on self-evaluation, or persistent lack of recognition of the seriousness of the current low body
weight.
Anorexia Purging What is the blood picture in frequent vomiting or use of diuretics?
Hypokalemia with an increased serum bicarbonate level
Anorexia Purging What is the blood picture in laxative abuse?
nonanion gap acidosis
Anorexia Wha are the 4 ways to calculate TGW?
Anorexia What are the criteria for Binge Eating Disorder? DSM 5
A. Recurrent episodes of binge eating. An episode of binge eating is characterized by both of the following:
- Eating, in a discrete period of time (e.g., within any 2-hour period), an amount of food that is definitely
larger than what most people would eat in a similar period of time under similar circumstances.
- A sense of lack of control over eating during the episode (e.g., a feeling that one cannot stop eating or
control what or how much one is eating).
B. The binge-eating episodes are associated with three (or more) of the following:
- Eating much more rapidly than normal.
- Eating until feeling uncomfortably full.
- Eating large amounts of food when not feeling physically hungry.
- Eating alone because of feeling embarrassed by how much one is eating.
- Feeling disgusted with oneself, depressed, or very guilty afterward.
C. Marked distress regarding binge eating is present.
D. The binge eating occurs, on average, at least once a week for 3 months.
E. The binge eating is not associated with the recurrent use of inappropriate compensatory behavior as in
bulimia nervosa and does not occur exclusively during the course of bulimia nervosa or anorexia nervosa.
Anorexia What are the ECG findings in anorexia?
- Classic teaching is QTc prolongation. EXAM>>
- Typically bradycardia & Increased QT dispersion (difference between the maximum QT interval and the minimum QT interval and reflects heterogeneous ventricular depolarization).
- Hypokalemia - < 3 mEq/L -ST segment sagging, T wave
depression, and U wave elevation.
- ECG usually has low voltage, with nonspecific ST or T wave
changes.
Anorexia What are the Fx and management of the female athlete traid?
Sx: low energy availability, menstrual dysfunction, and reduced BMD in female athletes
• caloric intake is insufficient for energy expenditure -> hypothalamic
amenorrhea (primary or secondary) -> low estrogen state
• Inv: Every female athlete with amenorrhea should have a complete
history and physical examination to evaluate for an underlying eating
disorder and to rule out other treatable causes of amenorrhea
• Treatment: increase caloric intake, calcium and vitamin D
supplementation, restricting the intensity of training (if necessary),
and monitoring for resumption of menses
Anorexia What are the indications for hospitalising an adolescent for anorexia? (5)
-
Growth:
a. TGW of < 75%
b. Arrested growth and development - FEN: Electrolyes low(PO4, K+, Na+) and dehydration
-
Physiological instability:
a. ECG- Long QTc or severe bradycardia
b. HR < 50 day/45 nocte; BP< 90/45; temp < 35.6; HR increase by 20/min
4. Management/behaviour:
a. Failure of OPD Rx
b. Acute food refusal/uncontrollable binging/purging
5. Medical issues:
a. Syncope, fits, pancreatitis, heart failure
b. psychiatric : Severe Depression, suicide, OCD, Type 1 DM
Anorexia What helps to decrease osteoporosis in adolescents with anorexia nervosa?
increase in body weight to within 10% of IBW
Anorexia What is TGW?
•Target Goal Weight (TGW) is the weight necessary to support:
- puberty, growth and development,
- physical activity and psychological and social functioning
Anorexia
- What is the ideal method of measuring target goal weight in this case?
- What setting should her initial management take place in?
- Using previous growth charts
- Outpatient setting (normal vitals, best %target goal weight >75%)
Are there any pregnancy or teratogenic risks with taking emergency contraception while already pregnant?
Nope!
ARFID Wha are the DSM 5 criteria to Dx ARFID?
A. An eating or feeding disturbance as manifested by persistent failure to meet appropriate nutritional and/or energy needs associated with one (or more) of the following 4 Fx:
B. The disturbance is not better explained by lack of available food or by an associated culturally sanctioned practice.
C. The eating disturbance does not occur exclusively during the course of anorexia nervosa or bulimia nervosa,
and there is no evidence of a disturbance in the way in which one’s body weight or shape is experienced.
D. The eating disturbance is not attributable to a concurrent medical condition or not better explained by
another mental disorder. When the eating disturbance occurs in the context of another condition or disorder,
the severity of the eating disturbance exceeds that routinely associated with the condition or disorder and
warrants additional clinical attention.
Breast problems What are the Fx of a breast cancer?
Breast problems What are the Fx of a breast cysts?
Breast problems What are the Fx of a fibroadenoma?
Contraception
Contraception How do the following forms of Emerg Contraception compare in etrms of Efficacy, pros and cons?
Yuzpe
Plan B
Ella
Copper IUCD
Notes:
- For Cu IUCD - the latest you can insert it is 7 days
- The Morning after pill/Plan B is same as Levonorgestrel
Contraception How would you counsel a teenager on contraception?
1. Conseling:
Start discussing sexual health, fertility and contraception in early adolescence in a colaborative approach
-
Contraception options:
a. Specific options
LARC’s IUD
Hormonal: OCP, injectable, patch, vaginal ring
Methods at time of intercourse: condoms (male/female), diaphragms, sponges, spermicides, cervical caps
b. Hx, BP, wt (ALL) .pelvic exam & STI screening only if needed
c. P_racticalities:_
- Give 12 mth Rx for hormonal options
- Ensure quick start option
- Offer technical advice eg condom usage
- Provide Emerg Contraception advice
Contraception What are the absolute contraindications to estrogen containing contraceptives?
A: Active liver disease (Liver tumor, hepatitis, severe cirrhosis)
B: Breastfeeding women < 6 weeks postpartum or
nonbreastfeeding <6 weeks with other risk factors for VTE
C:
a. Cancer: Current breast cancer
b. Cardiovascular; IHD, CVA, HTN >160sBP >100dBP, or vascular disease, Complicated valvular heart disease
c. Conditions; Migraine with neurologic symptoms (includes aura), Complicated solid organ transplant
D: DVT
a. VTE (Past and not on anticoagulant, past and high risk for
recurrent, acute DVT/PE, Major surgery with prolonged
immobilization)
b. Antiphospholipid antibodies positive or unknown (lupus)
Contraception
- What are the absolute contraindications for emergency contraception?
- When do you need to do a pregnancy test after EC?
- When should you repeat the EC dose?
- There are NO absolute contraindications to the use of emergency hormonal contraception except known pregnancy, and this is only because it is ineffective…
- Complete a pregnancy test if they do not experience normal menstrual bleeding by 21 days following EC treatment or by 28 days if an OCP was started after taking hormonal EC
- Repeat dose if vomit < 1 hour
Contraception What are the potential indications for the use of EC?
What factors put someone more at risk for developing a gambling problem? (6)
- Depression
- Loss
- Abuse
- Impulsivity
- Antisocial traits
- Learning disabilities
When screening for a gambling problems in adolescents, which questions should you ask?
- Frequency & Tendency to gamble more than planned (inability to respect personal limits)
- Hiding gambling behavior from other people (ie. lying)
- How are they doing in school?
- Sleep problems?
- Money or possessions in the home go missing? Theft?
- Substance use?
- Mood and Impaired relationships?
Gambling When should pediatricians screen for gambling?
Genital lesions What are the DDx for genital lesions?
- STD: HSV, Syphylis, Haemophilus ducreyi (chancroid)
- infection -Non STD: EBV, mycoplasma
- Diseases: Bechets, Crohns
How can an adolescent get Plan B? -dose?
It is available WITHOUT a doctor’s prescription across Canada! Obtain from pharmacist over the counter. -dose: two pills at once (each = 0.75 mg levonorgestrel)
HPV What 3 groups needs 3 doses of HPV vaccine?
- > 15 years + - catch up program
- If immunized with HPV-2 or -4 can repeat full 3 doses of HPV 9
- Immunocompromised/infected with HIV
HPV What 4 scenarios can HPV infection present with?
- Vertical transmission ‘juvenile-onset recurrent
respiratory papillomatosis’
- Asymptomatic
- Warts (HPV 6, 11) cause 90% genital warts
-
Malignancies-
- cervical/vaginal/ vulvar cancers
- penile and anal cancers
In individuals who begin indoor tanning before age 35, what is the increased risk of developing cutaneous malignant melanoma?
75% increased risk! -early life exposure has been associated with higher risks of CMM
In taking a history of the pregnant adolescent, what should you inquire about? (8)
- How has this pregnancy affected you physically and emotionally? 2. What is your knowledge of the options and how do you feel about them? 3. Are there any family, cultural or community issues that may play a role in your decision making? 4. How does your partner feel about the options and what is his role in your decision-making process? 5. Tell me about your support system. 6. PMHx? 7. High risk health behaviours/substance abuse 8. Housing/school status/personal and academic goals ****A good thing to say: “When you have an unplanned pregnancy, there is no perfect choice. All you can do is think about what is best for you at this time. No matter what option you choose, it is unlikely that you will feel it is 100% right”
In which age group is there the highest rate of STIs in Canada?
The highest rates of STIs in Canada are in the 15-24 year age group with girls 15-19 yo having the highest rate for chlamydia and gonorrhea
Menstrual problems in Downs Syndrome
One of your adolescent patients who is pregnant has decided to continue with her pregnancy. She comes to you for advice moving forward. What should you counsel? (4)
- Refer her to support groups/maternity homes/drop in centers 2. Encourage her to continue education to enhance potential for positive maternal and child outcomes and decrease social isolation/depression 3. Encourage if appropriate involvement/presence of baby’s father and/or current partner 4. Provide contraceptive counselling
One of your adolescent patients who is pregnant decides to terminate the pregnancy. What do you counsel her? (4)
- Give info about specific details about procedures available 2. Anticipatory guidance about common emotional responses: grief, relief, anger 3. Refer to appropriate medical/surgical services 4. Make f/u appointments to review any possible complications (bleeding/cramps/fever/physical and emotional concerns)
PCOS What are the clinical implications of PCOS?
1. Gynae:
Infertility
Dysfunctional bleeding
Endometrial carcinoma
2. Medical/diseases:
Obesity/T2DM/Dyslipidemia
Cardiovascular disease/Hypertension
PCOS What are the essential inv to Dx PCOS?
- Persistent elevation of serum total and/or free testosterone
- LH > FSH (2:1-3:1)
- Low LH suggests a hypogonadotropic disorder of neuroendocrine origin, whereas high FSH suggests primary ovarian failure
- Not diagnostic but helpful
- Dexamethasone androgen-suppression test - permits a positive diagnosis of the characteristic ovarian and adrenal dysfunction of PCOS
PCOS What are the inv for mimics?
- Pregnancy; Beta HCG
- U/S - ovarian imaging can be deferred during the diagnostic
evaluation for PCOS (remember this is a transvaginal study),
only reason would be to rule out a virilizing ovarian tumor if
suspected
3. Endocrine blood tests:
a. 17-OHP (r/o non classical CAH)
b. DHEAS - primarily to screen for an adrenal tumor
c. Prolactin
PCOS What are the PCOS Dx criteria?
-
Abnormal uterine bleeding pattern
a. Abnormal for age or gynecologic age
b. Persistent symptoms for one to two years -
Evidence of hyperandrogenism
a. Persistent testosterone elevation
b. Moderate-severe hirsutism and acne vulgaris-
indication to test for hyperandrogenemia
-
Exclusion of other causes
a. Nonclassic congenital adrenal hyperplasia (NCCAH), b.Cushing’s syndrome,
c. prolactin excess,
d. thyroid dysfunction, and acromegaly
PCOS What Inv to detect cplxns of PCOS?
-
Insulin resistance
a. Insulin resistance and hyperinsulinemia should not be utilized as diagnostic criteria
b. Insulin resistance and hyperinsulinemia can be considered as indications to investigate and treat potential comorbidities
c. Insulin resistance out of proportion to that conferred by obesity - Monitoring weight, height
-
Metabolic syndrome
- Monitoring - glucose, central (android) obesity, hypertension, and dyslipidemia
PCOS What is the management?
Guided by what px cares about!
-
Hyperandrogenism:
a. Hirsutism- Shaving, waxing, bleaching laser therapy,
electrolysis + Vaniqa (eflornithine)
b. Acne – same as regular acne management
c. Cutaneous hyperandrogenism-Combination OCP & Anti androgens
2. Gynae:
Periods-use the Combination OCP
a.Estrogen: Inhibit HPO axis, reduces ovarian
androgen production, increase SHBG
levels
b. Progestin: Inhibit proliferation
c. Also OCP does Normalize androgen levels
3. Metabolic management:
a. Lifestyle-Nutrition, exercise
b. Metformin for impaired glucose tolerance
- Insulin sensitizer & Inhibits hepatic glucose output
- Can suppress
Inhibits hepatic glucose output
• Can suppress appetite and enhance weight
loss
Risks What is the FISTS Mnemonic?
STI How do you Inv for Chamydia
- NAAT is the most sensitive and specific test. Can be performed on urine, urethral swabs, vaginal or cervical swabs*
- A culture of cervical or urethral specimen is the test of choice for medico-legal cases (eg, child abuse). Confirmation by NAAT using a different set of primers or DNA sequencing may be used
N.B. Serology should not be used for diagnosis
STI When do you do test for cure for Chlamydia?
NAAT 3-4 weeks after Tx
- Prepubertal/Pregnancy
- Uncertain compliance/Likely re-exposure
- Alternative treatment
STI STI When do you do test for cure for Gon?
Culture 3-4 days
-
Risk factors;
- Prepubertal/Pregnancy
- High re-exposure risks
2. Treatment related:
- Second-line or alternative treatment is used
- Antimicrobial resistance is suspected
- Previous treatment has failed
Pharyngeal infection signs or symptoms
persist following treatment
STI How do you Inv for Gonorrhea?
- NAAT can be used to detect gonorrhea from urine, and urethral, vaginal and cervical swabs in symptomatic and asymptomatic individuals*
-
Culture allows for antimicrobial susceptibility testing and should be performed if a patient does not promptly respond to therapy, given concerns regarding antimicrobial resistance
a. Cultures should be submitted for asymptomatic or symptomatic MSM, who have an increased incidence of antibiotic resistance
b. Culture preferred for throat specimens
c. For medico-legal purposes, a positive result obtained from NAATs should be confirmed using culture or a different set of primers, or by DNA sequencing techniques
STI How do you Rx uncomplicated gonococcal and chlamydial co-infection?
Anogenital infections (urethral, endocervical, vaginal, rectal)
STI What counseling do you give after STI Rx and starting sexual intercourse again?
- Abstain from sexual intercourse for 7 days after single-dose therapy or until completion of a 7-day regimen and resolution of symptoms if present.
- To minimize risk for reinfection, patients also should be instructed to abstain from
sexual intercourse until all of their sex partners are treated
STI What samples should be collected for asymptomatic females with risk factors?
- For Chlamydia & gonorrhoeae- First-catch urine or
Vaginal swab - Serology for:Syphilis, HIV
3. Other **serological tests** to consider: Hepatitis A (particularly with oral-anal contact) Hepatitis B (if no history of vaccine) Hepatitis C (particularly in an injection drug user
STI What samples should be collected for asymptomatic males with risk factors?
- For Chlamydia & gonorrhoeae- First-catch urine or
Urethral swab - Serology for:Syphilis, HIV
3. Other **serological test**s to consider: Hepatitis A (particularly with oral-anal contact) Hepatitis B (if no history of vaccine) Hepatitis C (particularly in an injection drug user)
STI What samples should be collected for females with Sx of cervicitis?
- Vaginal or cervical swab for Gram stain, N gonorrhoeae culture and C trachomatis (NAAT or culture)
- Swab of cervical lesions (if present) for herpes simplex virus
- Vaginal swab for wet-mount
STI What samples should be collected for males with Sx of urethritis?
Urethral swab for Gram stain and culture for gonorrhea (NAAT may also be used where available)
AND
First-catch urine for C trachomatis (NAAT)
STI What tests for Suspected pharyngeal gonococcal infection?
Swab the posterior pharynx and the tonsillar crypts
Use the swab to directly inoculate the appropriate culture medium, or place it in a transport medium
STI Who shoul dbe screened for STI’s?
True or false: children’s firearm safety education programs are effective in reducing firearm injury rates in children. -reasons for why or why not? (2)
FALSE. There has been no evidence so far that these programs help. Lots of studies have shown they don’t make a difference and that if a kid sees a gun, 50% will touch it, 50% will not regardless of whether they’ve been educated or not. Reasons why not: 1. Firearm safety education for children may increase their comfort level around guns (especially ones that include gun handling techniques) 2. Parents may have false sense of security and reduce their supervision or use of safe storage practices if they think their child learned gun safety at school
Wha are the Fx of the feeding disorder in ARFID?
An eating or feeding disturbance (e.g., apparent lack of interest in eating or food; avoidance based on the
sensory characteristics of food; concern about aversive consequences of eating) as manifested by persistent
failure to meet appropriate nutritional and/or energy needs associated with one (or more) of the following:
- Significant weight loss (or failure to achieve expected weight gain or faltering growth in children).
- Significant nutritional deficiency.
- Dependence on enteral feeding or oral nutritional supplements.
- Marked interference with psychosocial functioning.