Cp 13 Basics of transport Flashcards
Is K+ or Na+ higher inside the cell
Intracellularly K+ concentration is higher
Is K+ or Na+ higher on the outside of the cell
Extracellularly Na+ concentrations are greater than K+
[Na+] > [K+] out side of the cell T or F
True
[K+] > [Na+] inside the cell T or F
True
Glucose is > outside the cell than in T or F
True
Intracellularly proteins are found in greater concentrations T or F
True
In simple/passive diffusion what is the rate dependent on?
the degree of lipid solubility - there is no pore of protein channel so the molecule being transported must go through the lipid bilayer
in facilitated diffusion ______ and ____ determine the selectivity of the pore or channel
pore diameter and electrical charges on the AAs
What types of molecules use facilitated diffusion
water and other lipid insoluble compounds must use protein channels
What type of diffusion channel is regulated by chemicals that bind channel proteins
ligand gated
What channel contains pore loops that act as a selectivity filter for K+
Potassium channels
Sodium channels are lined with highly positive amino acids and have an opening that is 0.3-0.5 nm in diameter T or F
False - they are lined with highly negative amino acids that attract sodium though they do have an opening that is 0.3-0.5 nm in diameter
Addition of more substrates that rely on facilitated diffusion/carrier proteins will increase the rate of transport T or F
False. Transport proteins can only move what they can bind. If all available transport proteins are bound to substrate the protein has hit it’s Vmax
Does facilitated diffusion use ATP?
NO
Km = ?
the solute concentration that will give 1/2 the Vmax of a transport protein