Corticosteroids - Mineralcorticoids

Question 1

There are 3 layers to the adrenal glands:

• zona glomerulus
• zona fasiculata
• zona reticularis

Match the above layers with what they synthesise and release?

• glucocorticoids
• androgens
• mineralcorticoids

Answer 1

• zona glomerulus =
• mineralcorticoids
• zona fasiculata = glucocorticoids
• zona reticularis = androgens

The deeper you get the sweeter it gets

Question 2

Where in the adrenal gland is adrenaline and noradrenaline synthesised and released?

1 - zona glomerulus
2 - zona fasiculata
3 - medula (chromaffin cells)
3 - zona reticularis

Answer 2

3 - medula (chromaffin cells)

Question 3

Steroids are typically cholesterol based, meaning they are lipophilic. This means that are able to diffuse into cells freely. Once they pass into the cell they are able to elicit actions. Organise the following into what happens within the cells?

1 - diffuse into cell membrane due to small size and hydrophobic nature
2 - cell undergoes transcription and protein synthesis
3 - hormone receptor complex enters the nucleus and cytoplasmic receptor aspect of the hormone receptor complex binds to DNA
4 - steroid hormone binds with cytoplasmic receptor forming hormone receptor complex
5 - hormone receptor complex binds to specific parts of DNA and genes can be turned on or off

Answer 3

1 - diffuse into cell membrane due to small size and hydrophobic nature

4 - steroid hormone binds with cytoplasmic receptor forming hormone receptor complex

3 - hormone receptor complex enters the nucleus and cytoplasmic receptor

5 - hormone receptor complex binds to specific parts of DNA and genes can be turned on or off

2 - cell undergoes transcription and protein synthesis