Corticosteroids

Question 1

Endogenous steroids are produced by which organ?

Answer 1

Adrenal gland, gonads and placenta

Question 2

What are the two classes of corticosteroids?

Answer 2

Glucocorticoids and Mineralcorticoids

Question 3

Function of Gluococorticoids

Answer 3

Increase carb, protein and fat metabolism
growth (specifically in utero)
increase contractile activity of left ventricle
signal kidneys to reabsorb sodium
inhibit activity of cells that are used to promote connective tissue production
alter turnover of bone
stop GI from absorbing calcium and promote calcium excretion from kidney
Inhibit formation of prostaglandins and bradykinins -> inhibit inflammation
suppress white blood cells (lymphocytes and eosinophils)