Cortical Syndromes Flashcards

1
Q

Which hemisphere is dominant for language?

A

Left hemisphere

  • in >95% of righties
  • in 60-75% of lefties
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2
Q

Location of Wernicke’s area

A

posterior 2/3 of the superior temporal gyrus of the dominant hemisphere

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3
Q

Function of Wernicke’s area

A

identification of sounds and comprehension of meaningful words

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4
Q

Location of Broca’s area

A

in the opercular and triangular portions of the inferior frontal gyrus of the dominant hemisphere

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5
Q

Function of Broca’s area

A

articulation of sounds that constitute speech

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6
Q

What is the arcuate fasciculus?

A

Subcortical white matter pathway that connects Wernicke’s and Broca’s area to allow to hear and repeat a word

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7
Q

Aphasia

A

= language defect due to dysfunction in the dominant cerebral hemisphere

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8
Q

Most common cause of Broca’s aphasia

A

frontal lobe lesions

-infarct of left MCA (middle cerebral artery) superior division

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9
Q

Broca’s aphasia

A

Expressive aphasia

  • decreased fluency of spontaneous speech
  • aware of deficit
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10
Q

Most concomitant finding associated w/ Broca’s aphasia

A

Right hemiparesis (weakness of right face/arm)

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11
Q

Most common cause of Wernicke’s aphasia

A

Temporal lobe lesion

-infarct of left MCA (middle cerebral artery) inferior division

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12
Q

Wernicke’s aphasia

A

Receptive aphasia

  • impaired comprehension
  • no meaningful content of speech- just jargon
  • pts are not aware of the deficit
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13
Q

Most concomitant finding associated w/ Wernicke’s aphasia

A

Contralateral visual field cut

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14
Q

What is alexia w/o agraphia

A

Can write normally, but can’t read

=disconnection syndrome- caused by disconnection of the right and left hemispheres due to interruption of the corpus callosum

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15
Q

Cause of alexia w/o agraphia

A

lesion in the dominant occipital cortex extending to the posterior corpus callosum
-most often from PCA infarct

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16
Q

What is apraxia?

A

Inability to perform learned motor tasks

ex: can’t put a shirt on or salute the flat

17
Q

What is hemineglect syndrome?

A

Neglect for the contralateral half of the external world

18
Q

Most common cause of hemineglect syndrome

A

Lesions of the right parietal or frontal cortex

-most specifically associated w/ damage to the temporo-parietal junction and posterior parietal cortex

19
Q

What is limbic encephalitis?
Cause?
Associated w/ what?

A

Autoimmune inflammation of the brain

-caused by autoimmune often (but not always) associated w/ cancer

20
Q

Most common presentation of limbic encephalitis

A

Short term memory deficits

-also psychosis, headache, seizures

21
Q

What is alien hand syndrome?

(a) where is the lesion?

A

Involuntary movements of the contralateral arm

(a) lesion of the parietal lobe