Conferences/Rapidfire Flashcards
Example of how to test attention
Ask for days of the week backwards
Triad for LBD
Parkinsonism + prominent dementia + visual hallucinations
How to distinguish LBD from Parkinsons disease dementia
LBD has visual hallucinations and fluctuations, PDD does not
Evidence of vascular dementia on MRI
Decrease in white matter
Distinguish vascular dementia from Alzheimer’s
Vascular dementia usually a step-wise decline in cognition, specific events (lacunar strokes) associated w/ significant declines
While AD has more of a gradual cognitive decline
Timeline of prion disease
Decrease of cognition w/in weeks
Two infectious causes of dementia
Syphilis and HIV
Intoxication cause of dementia
Wernicke-Kosakoff (B1 deficiency due to chronic alcoholism)
How can trauma cause dementia
TBI => axonal shearing
What parts of the brain are involved in working memory vs. forming new memories
- Problems in frontal lobe => problems w/ working memory
- Problem in hippocampus => problems forming new memories
Two Parkinsonian plus syndromes w/ eye involvement
- PSP (progressive supranuclear palsy): vertical gaze palsy
- MSA (multiple system atrophy): autonomic dysregulation
Clinical Hallmark of PSP
- vertical gaze palsy
- falls
Clinical Hallmark of MSA
Dysautonomia (autonomic dysregulation)
Clinical Hallmark of CBD
CBD = corticobasal ganglionic degeneration
Hallmark = alien limb
What non-Parkinsonian cause of dementia
Wernicke-Korsakoff = 6th nerve palsy
Clinical Hallmark of Wernicke-Korsakoff
6th nerve palsy + confabulation (making shit up)
Clinical Hallmark of NPH (normal pressure hydrocephalus)
Dementia, urinary incontinence, magnetic gait
What is magnetic gait? What is it indicative of?
Magnetic gait = can’t lift legs off the floor (so basically shuffle w/ feat on the floor)
-indicative of normal pressure hydrocephalus
Speech problem w/
- good comprehension
- non-fluent speech
- poor repetition
Broca’s aphasia