Coronaviridae

Question 1

Largest nonsegmented rna viruses

Answer 1

Coronaviruses

Question 2

Characteristic of. Corona virus

Answer 2

Non segmented rna
Enveloped
Pleomorphic
Club shaped spikes

Question 3

Genome of coronavirus

Answer 3

Positive sense linear single. Stranded rna

Replicate in cytoplasm

Question 4

Genetic variant of transmissible gastroenteritis virus

Answer 4

Porcine

Respiratory corona virus

Question 5

Transmission of transmissible gastroenteritis

Answer 5

By fecal oral transmission

Question 6

Pathogenesis of transmissible gastroenteritis

Answer 6

Virus selectively affects enterocytes lining intestinal villi
Not crypts

Question 7

Aftereffects of enterocytes infected

Answer 7

Malabsorption
Malnutrition
Acidosis
Dehydration

Question 8

Clinical signs of transmissible gastroenteritis

Answer 8

Diarrhoea vomiting
Rapid weight loss
Dehydration
Incubation period 18 to 72 hours

Question 9

Lesions are

Answer 9

Distended stomach
with undigested milk gas
Fluid distended intestine

Question 10

Lab diagnosis

Answer 10

Isolation in cell culture pig kidney testis cell culture

Question 11

Finding in cell culturr

Answer 11

Cell rounding synctitia formation

Question 12

Control

Answer 12

Orally administering virulent viruses to pregnant sow
IgA antibodies through colostrum

Proper sanitation of surroundings