adenovirus Flashcards

1
Q

structure

A

double stranded
linear
cubical symmetry
252 capsomeres

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2
Q

what is penton fibre

A

from the vertex fibre like protein projects with a knob

responsible HA property of virus

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3
Q

pentone fibres bifurcated in

A

avian adeno virus

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4
Q

classification of adeno virus

A

mastedeno
aviadeno
atadeno

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5
Q

mastedeno virus has

A

CAV I rubarth disease

CAV II infectious canine tracheobronchitis

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6
Q

aviadeno virus causes

A

IBH
HPS
quail bronchitis virus

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7
Q

atadenovirus has

A

EDS virus (egg drop syndrome)

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8
Q

what E1A and E1B Do

A

shut down cellular p53 gene

which suppresses tumours

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9
Q

E3 gene get replaced with

A

gene sequence of other viruses

insertion site for foreign dna or live vectors

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10
Q

adenovirus has…….effect

A

cytopathic effect

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11
Q

infectious canine hepatitis/rubarth disease /blue eye

A
virus ingested
then multiplies in peyers patches
primary viremia
then to liver lungs kidney
eventhough virus neutralises urine sheds viruses for 6 months
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12
Q

clinical signs signs of rubarth disease

A

acute hepatitis
fever
loss of apetite
blood tinged diarrhoea

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13
Q

lesions of rubarth disease

A
hepatomegaly
inclusion bodies
inflammation of glissons capsule
inclusion bodies in brain
paint brush appearence in  stomach and intestine because of haemorrhages
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