adenovirus Flashcards
structure
double stranded
linear
cubical symmetry
252 capsomeres
what is penton fibre
from the vertex fibre like protein projects with a knob
responsible HA property of virus
pentone fibres bifurcated in
avian adeno virus
classification of adeno virus
mastedeno
aviadeno
atadeno
mastedeno virus has
CAV I rubarth disease
CAV II infectious canine tracheobronchitis
aviadeno virus causes
IBH
HPS
quail bronchitis virus
atadenovirus has
EDS virus (egg drop syndrome)
what E1A and E1B Do
shut down cellular p53 gene
which suppresses tumours
E3 gene get replaced with
gene sequence of other viruses
insertion site for foreign dna or live vectors
adenovirus has…….effect
cytopathic effect
infectious canine hepatitis/rubarth disease /blue eye
virus ingested then multiplies in peyers patches primary viremia then to liver lungs kidney eventhough virus neutralises urine sheds viruses for 6 months
clinical signs signs of rubarth disease
acute hepatitis
fever
loss of apetite
blood tinged diarrhoea
lesions of rubarth disease
hepatomegaly inclusion bodies inflammation of glissons capsule inclusion bodies in brain paint brush appearence in stomach and intestine because of haemorrhages