COPD Q3 Flashcards

1
Q

In obstructive pulmonary dx what (2) factors increase

A

Total Lung Capacity
Residual Vol

(all else decreases)

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2
Q

In restrictive pulmonary dx what factor increases

A

FEV 1sec/ FVC

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3
Q

during emphysema there is a permanent _____ of the airspaces ____

A

permanent enlargement

airspaces distal to teh terminal non-respiratory bronchioles

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4
Q

Incidence of Emphysema

A

age 50

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5
Q

pink puffers are ___cc

A

emphysema

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6
Q

(2) predisposing factos of emphysema

A

smoking

alpha-1 antitrypsin deficiency

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7
Q

The AP diameter is increased in ___ cc

A

emphysema

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8
Q

is emphysema alkalosis or acidosis

A

alkalosis

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9
Q

what are the conditions that have to be seen to diagnosis chronic bronchitis

A

excessive sputum production for at least three mo. for two consecutive yrs

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10
Q

incidence of chronic bronchitis

A

after age 32

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11
Q

blue bloaters

A

chronic bronchitis

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12
Q

(2) predisposing factors

A

smoking

air pollution

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13
Q

breath sounds of chronic bronchitis

A

wheeze

rhonci

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14
Q

(3) cc that are a part of COPD

A

chronic bronchitis
emphysema
Chronic bronchial asthma

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15
Q
chronic bronchitis leads to:
Mucous gland \_\_\_\_
excess \_\_\_\_ production 
\_\_\_\_\_\_ cell hyperplasia 
Incr \_\_\_\_\_ Ration 
\_\_\_\_ atelectasis
A
hyperplasia 
excess mucous 
goblet cell hyperplsia 
increase reid index 
patchy atelectasis
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16
Q

_____: ratio of the thickness of the submucosal gland layer to the bronchial wall

A

increase reid Index

bronchitis

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17
Q

***Bronchitis can be a predisposing factor to ___ cc

A

cancer

squamous metaplasia

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18
Q

*** what is the most common type of emphysema

A

centrilobular emphysema

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19
Q

WHat structures does the centrilobular emphysema affect?**

A

proximal respiratory bronchiole
- spares the alveolar duct and alveoli

( the “central part”

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20
Q

____ emphysea is common in coal workers pneumoconiosis and smokers

A

centrilobular

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21
Q

____ emphysema involves the alveolar duct and alveoli but spares the prox respiratory bronchioles

A

paraseptal emphysema

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22
Q

____: air trapped in dilated spaces below the pleura

A

subpleural bulae

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23
Q

___: air trapped in spaces btw layers of the pleura

A

blebs

responsible for spontaneous pneumothorax

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24
Q

family hx is present in ___ bronchial asthma

A

extrinsic

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25
Q

skin test is ___ for extrinisic astha

A

positive

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26
Q

___ asthma is present in children **

A

extrinsic

can grow out of it

27
Q

___: whorls of shed epithelium in asthma

A

curschmann’s spirals

28
Q

____: crystalloid of eosinophilic membrane protein in asthma

A

charcot - leyden crystals

29
Q

cc_____: characterized by a horse, high pitched cough

A

acute largyngeotrachitis

30
Q

*** etiology of acute laryngeotrachitis

A

MCC is streptococcus
haemophilus
or viruses

31
Q

cc___: inflam at all levels of the bronchial tree

A

bronchitis

32
Q

*** pathology of bronchitis

A

exudative infiltrate of neutrophils and fibrin due to chems, bacteria, viruses, cell infiltration, and congestion

33
Q

*** cc_____: a patchy consolidation of acute inflammation arising in the bronchus and extending focally into the lung

A

bacterial pneumonia

34
Q

*** MCC organisms that cause acquired pneumonia is ____

*** MCC organism that causes nosocomial pneumonia is ____

A

acquired: streptococcus pneumonia in 80%

Nosocomial: E. Coli and pseudomonas

35
Q

MC location of bacterial pneumonia

A

lower lobe

Liquefactive necrosis

36
Q

*** cc____pneumonia: involved entire lobe of a lung and is NOT patchy

A

Lobar pneumonia

37
Q

*** most common bact. that affects lobar pneumonia

A

streptococcus pneumonia

38
Q

***What is the most serious stage in lobar pneumonia pathology

A

stage of red hepatization (2-4 days) : dry and firm, red protein exudate has lots of neutrophils.

39
Q

MC cause of walking pneumonia

A

Atypical pneumonia (mycoplasma pneumoniae)

40
Q

*** MCC of atypical pneumonia

A

mycoplasma pneumonia

41
Q

***cc____: chronic necrotizing infection of the bronchi and bronchioles with a permanent abnormal bronchial dilation (suppurative)

A

bronchiectasis

42
Q

***Location of beonchiectasis

A

lower lobe

43
Q

Describe Kartagner’s sx that is seen in bronchiectasis

A

bronchiectasis
sinusitis
sutus inversus

44
Q

*** Name 4 bronchiectasis clinical findings

A

cough
fever
foul smelling purulent sputum
clubbing fingers

45
Q

cc___: aspiration of infected material will cause a local suppurative process within the parenchyma

A

pulmonary abscess

occurs in the L. lung

46
Q

***The initial focus of primary TB is called ___ in the upper part of the lower lobes or the lower part of the upper lobes

A

Ghon Focus

in the hilar nodes

47
Q

*** location of secondary TB

A

apex

48
Q

***secondary TB is called ___

A

miliary TB

49
Q

*** cc___: occurs in large river valley of Midwest and eastern US.

A

histoplasmosis

histoplasma capsulatum fungus

50
Q

cc___: diffuse pulm dx characterized by leaky pulm cap’s proteinaceous deposits in alveoli and atelectasis

A

adult respiratory distress sx (ARDS)

51
Q

*** MCC of adult respiratory distress sx (ARDS)

A

septis

52
Q

***CC__: collapse of alveoli by obstruction of the airway or the failure of complete expansion of the lung at birth.

A

atelectasis

53
Q

***CC____: hyaline membrane disease. Affects infants with predisposing factors (prematurity, prenatal asphyxia, or babies w/ diabetic mothers)

A

neonatal respiratory distress sx

decr in pulm surfactant leads to atelectasis

54
Q

***Cc____: decr in pulm surfactant leads to atelectasis

A

neonatal respiratory distress sx

55
Q

*** _____: coal worker or black lung disease due to deposition of coal dust

A

anthrascosis

56
Q

***_____: affects shipyard workers, insulation, and roofing workers who inhale fibers. Damage to lung pleura.

A

asbestos

57
Q

***_____: (hypersensitivity pneumonitis) type III hypersensitivity immune complex

A

farmers lung

58
Q

**MC primary cancer is ____

A

adenocarcinoma

59
Q

*** smokers get ____ carcinoma

A

squamous cell carcinoma

60
Q

What is the overall most common type of lung cancer

A

metastatic

61
Q

*** small oat cell carcinoma has secretory products such as (4)

A

beta lipotropine
ACTH
ADH
Serotonin

62
Q

*** What cancer is associated with asbestos exposure

A

malignant mesothelioma

63
Q

*** lung is encapsulated by thick, firm, white pleural tumor tissue called ____ or _____ that metastasize to lymph nodes and liver.

A

psammoma bodies or onion ring