Ch 2 Cardio Inflammatory Dx Flashcards

1
Q

_____: recurrent inflam. (AI dx) Ass. w/ group A beta-hemolytic streptococci w/ M protein of the pharynx

A

Rheumatic Heart dx

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2
Q

Who is effected by Rheumatic heart dx

A

children 5-15yr

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3
Q

___: host develops antibody against M-protein of streptoccus

A

Rheumatic Heart dx

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4
Q

What are aschoff bodies

A

lesions located in myocardial CT

in rheumatic heart dx

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5
Q

what dx is ass. w/ aschoff bodies

A

rheumatic heart dx

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6
Q

Which heart inflam dx effects all three layers of the heart= pancarditis

A

Rheumatic heart dx

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7
Q

endocarditis involves ___ anatomical structure on the heart

A

mitral valve

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8
Q

Acute rheumatic dx leads to ____

A

mitral regurgitation during systol

chronic- stenosis

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9
Q

Chronic Rheumatic dx leads to ___

A

stenosis

acute= mitral regurgitation

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10
Q

What valve does Endocarditis most likely effect

A

mitral valve

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11
Q

___ is the most common cause of mitral valve stenosis

A

endocarditis

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12
Q

What are the 5 jones critieria for Rheumatic heart hc

A
  1. Carditis
  2. Migratory polyarthritis
    3 Subcutaneous nodules
  3. Erythema marginatum
  4. Rheumatic chorea
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13
Q

___: aschoff bodies in the myocardium

A

myocarditis

appears soft/ flabby/ dilated

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14
Q

____: bread and butter appearance with deposition of fibrin btw visceral and parietal layers

A

fibrinous pericarditis

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15
Q

______: plaques with clear center in the skin during rheumatic fever

A

erythema marginatum

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16
Q

______: over extensor surface made of giant aschoff bodies during rheumatic fever

A

subcutaneous nodules

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17
Q

____ stage of carditis can cause death during rheumatic fever

A

myocarditis

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18
Q

____: inflam of the myocardium

A

myocarditis

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19
Q

myocarditis is due to what virus

A

coxsackie B

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20
Q

The edema in myocarditis has ___cytes (not ___)

A

has lymphocytes (not neutrophils)

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21
Q

Asymptomatic myocarditis leads to what (3) conditions

A

fever
dyspnea
death

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22
Q

If a pt recovers from myocarditis it will led to: cc

A

congestive (dilated) cardiomyopathy

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23
Q

_____: dilated heart w. impaired contractibility

A

congestive cardiomyopathy

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24
Q

incidence of congestive cardiomyopathy

A

young adults

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25
_____: hypertrophy of the septum and LV , reduced LV chamber
hypertrophic cardiomyopathy
26
hypertrophic cardiomyopathy etiology____
autosomal dominant - congenital | seen in young adults when they become active
27
___ cardiomyopathy can lead to "sudden death" in a young athlete
hypertrophic cardiomyopathy
28
____: cardiomyopathy will cause a decrease in compliance. This will lead to incr filling resistance , Decr CO
restrictive cardiomyopathy
29
accumulation of iron can cause ____ cardiomyopathy
restrictive cardiomyopathy | hemochromatosis coloring
30
___ cardiomyopathy will have hemochromatosis coloring
restrictive cardiomyopathy - to much iron in the blood
31
who is hemochromatosis most often seen in
Males
32
(4) conditions seen in restricitve cardiomyopathy
1. amyloidosis 2. hemochromatosis 3. Loeffler's endocarditis 4. Endocardial fibroelastosis
33
(3) types of cardiomyopathy
congestive hypertrophic restrictive
34
(2) types of bacterial endocarditis
1. acute bacterial endocarditis (ABE) | 2. subacute bacterial endocarditis (SBE)
35
______: invasion of valves by microbial
bacterial endocarditis
36
____ bacterial endocarditis is often seen in IV drug users
acute bacterial endocarditis
37
______ is the bact. etiology of acute bact. endocarditis
staphylococcus aurus
38
Which has a higher mortality rate: subacute or acute bact. endocarditis
acute: 30% subacute: 60%
39
Which valve is effected by acute bact. endocarditis
tricuspid
40
___ bact. is the etiology for subacute bacterial endocarditis
streptococcus viridans (dentist can't work on ppl who have had previous heart conditions bc of this virus- pt needs to take an antibiotic before)
41
name the 2 non-bacterial endocarditis conditions
libman's sacks endocarditis | Marantic endocarditis
42
Libman's sack endocarditis is seen in pt with ___
SLE
43
maramtoc endocarditis is seen in pt with ___ sx
paraneoplastic sx
44
*** Left anterior descending artery supplies?-
the anterior wall of the left ventricle, apex of heart, and anterior 2/3 of the interventricular septum.
45
***____ is the main cause of Coronary ischemic Heart dx
atherosclerosis
46
*** What is the mech. of Prinzmetal's angina?
vasospasm of the coronary vessels due to release of thromboxane A2 form platelet thrombi
47
*** What is the #1 cause of MI
atherosclerosis
48
*** What is a transmural infarction?
affects the endocardium, myocardium and pericardium
49
***What is the MC location of MI
left anterior descending artery | - affects M on the anterior wall
50
***___-__% of MI end in sudden death within 2-4 hrs, and __% of MI cases are asymptomatic
35-40% death | 25% = asymptomatic
51
*** arrhythmias MCC of death is ____
ventricular extrasytols
52
cc_____: reduction of O2 blood to the myocardium
Coronary ischemic heart dx
53
cc____ infarction : is a MI that only affects the myocardium
subendocardial infarction
54
cc____ infarction: MI that affects the endo/myo/and pericardium
transmural infarction
55
``` cc______: the Lab test are high in: o CK-MB o LDH-1 o SGOT o Troponin ```
MI
56
cc___: is ass w/ L. ventricular hypertrophy → myofibrils incr w/ hyperchromatic nuclei
hypertensive Heart dx
57
*** Rheumatic heart dx have ____ lesions located in the interstitial myocardial CT
aschoff bodies
58
*** name / describe the three stages of aschoff bodies in rheumatic heart dx
1. early exudative phase w/ fibrinoid degeneration 2. classic phase: anitschkows myocytes & multinucleated aschoff giant cells 3. late phase: progressive fibrosis
59
***What is the cause of myocarditis in rheumatic heart dx
aschoff bodies
60
CC_____: connection of the pulm art. to the aorta
patient ductus arteriosis (PDA)
61
*** in a patient ductus arteriosis (PDA), a failure of the shunt ot close causes(4) :
L ventricular hypertrophy machinery murmurs pulmnary hypertension R. ventricular hypertrophy
62
***cc_______ defect: causes an opening in the communication btwn LA and RA with left to right shunt.
Atrial septal defect (ASD)
63
*** Name the three types of Atrial septal defect (ASD)
1. Ostium Primum: downs syndrome 2. Ostium Secumdum: foramen ovale (most common) 3. Sinus venosus
64
*** ____ is the most common congenital heart dx in adults
atrial septal defect (ASD)
65
***cc_____: defect in interventricular septum with shunting of blood from left to right
ventricular septal defect aka: eisenmenger's complex when it is cyanotic
66
*** is the MC congenital acyanotic shunt defect
ventricular septal defect (VSD)
67
*** Name the four abnormalities of tetralogy fallot
ventricular septal defect R ventricular hypertrophy pulm stenosis over riding aorta
68
What is the worst kind of cyanotic shunt defects
Eisenmenger's complex: ventricular septal defect and pulm hyperension changes from acyanotic (ventricular septal defect) to cyanotic
69
*** Location of primary cardiac myxoma
L atrium
70
*** (b) tumor of the heart
cardiac rhabdomyomas infants--> autosomal dominant ass w/ retard.
71
*** cc____: most common malignancy of the heart, direct extension from primary sites in the breast, lung or lymph nodes (malignant lymphoma).
metastic