Control of ecto and endo parasites Flashcards
Non chemical measures for GIN
- grazing management
- using immunity to worms
- genetic selection for resistance
- vaccination (not yet)
- integrated strategic drenching programs
Factors: Age
young animals get more worms, suffer more serious disease and shit out more eggs onto pasture
Grazing history
Animals exposed to heavily infected pastures get more worms
Climate
The weather affects which worm species are found in a locality. Warm, wet weather advantages parasites to develop and survive on pasture
breed
Some breeds and lines of sheep inherently carry fewer worms
Nutrition
Improved nutrition can reduce worm numbers and production costs of worms by boosting resistance
Immunity/resistance
Sheep develop immunity as they age. Older (immune) sheep carry fewer and suffer less from disease
Principles of worm control
- Worm life cycle and pasture numbers; warm and moist conditions enhance build-up and survival
- survival of L3 on pasure- extremes are usually lethal. Warm to hatch, cool to dry
- L3 don’t feed. Sooner or later run out of energy- faster w warmth
- rainfall zones
IPM strategies PxE
- Reducing development of parasite eggs on pasture
- Minimising infective stages (L3) available for infection
- Minimising infective (L3) ingested
IPM strategies HxP
- Minimising worms establishing and completing life cycle w egg production
- minimising eggs coming out of hosts
- maintaining host production (minimising prod. losses)
- Checking to ensure it is working
Grazing management: Strategies for reducing pasture contamination
- Spelling for 3-6 months esp over summer
- Cropping, forage, bushfires
- Grazing w adults or a different species (not goats)
- Keep pasture long, strip grazing
- Drench, hold and move to low L3 pasture
Innate immunity
30% of worms don’t establish in naiive lambs due to steroid sensitivity
Inflammation
worms don’t like a hostile location- inflammatory mediators expel worms
Acquired immunity
- allergic TH2- type responses are involved in protection
- induction of immunity is worm-specific, effector phase is non-specific (inflammatory mediators), expelling unrelated worms in same location
Breeding for resistance
- animals can be selected for resistance
- reduced epg is correlated w increased bodyweight