control of cardia output I Flashcards

1
Q

cardiac output =

A

heart rate x stroke volume

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2
Q

what is cardiac output CO

A

the volume of blood ejected bty each ventricle per minute

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3
Q

what is heart rate HR

A

the number of contractions (beats) per minute

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4
Q

what is stroke volume SV

A

the volume of blood ejected by each ventricle per beat

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5
Q

compare the cardiac output of an athlete to a non athlete

A

a non athlete has a greater resting cardiac output, a lower resting heart rate and produces a greater cardiac output when exercising

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6
Q

three pathways of innervaton of the heart

A

blood volume reflexes
autonomic
sympathetic via adrenal glands

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7
Q

describe blood volume reflexes

A

baroreceptors in the wall of carotid artery and carotid body chemoreceptor travel along sensory nerve fibers to the cardioregulatory center and chemoreceptors in the medulla oblongata

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8
Q

describe autonomic innervation of the heart

A

involuntary
parasympathetic nerve fibers end at the SAN. acetylcholine from vagus nerve
sympathetic nerve fibres hit the SAN and travel across the ehart. noradrenaline

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9
Q

describe innervation of the heart via the adrenal glands

A

sympathetic

signal comes out cns to adrenal medulla, produces adrenaline and noradrenaline

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10
Q

what is meant by chronotropic

A

increases the heart rate, cuts donwn the time that the SAN rests

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11
Q

what does an increase in heart rate do to cardiac output

A

increases it

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12
Q

what effect do noradrenaline and adrenaline have on the heart

A

positive chronotropic
stimulates the hyperpolarisation of ion channels at the SAN so more action potentials
(there is reduced repolarisation so the peak goes back up faster)

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13
Q

what effecr does acetylcholine have on heart rate

A

slows it, ie negative chronotropic
shifts the threshold for an action potential to more hyperpolarise potentials via activated K+ channels to hyperpolarise.

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14
Q

why do trained atheltes have lower heart rates

A

increased vagal tone

vagus nerve releases acetylcholine

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15
Q

tachycardia

A

fast heart rate

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16
Q

bradycardia

A

slow heart rate

17
Q

what is the end diastolic volume

A

the volume of blood in the ventricle at the end of loading or filling

18
Q

what is end systolic volume

A

the volume of blood at the end of a contraction and beginning of a filling
is the lowest volume of blood in the ventricle at any point in cardiac cycle

19
Q

what is the formula for stroke volume

A

EDV-ESV

end diastolic volume - end systolic volume

20
Q

what factors affect the end diastolic volume

A

preload- the amount of blood returned to the atria
contractility- the processes that control contraction of the heart
afterload- the resistance the blood faces as it leaves the ventricle

21
Q

what does preload depend on

A

the filling of the ventricles depends on the atrial filling which is determined by central venous pressure or venous return

22
Q

what does an increase in end diastolic volume lead to

A

an increase in the initial length of the cardiac muscle fibres (they become stretched) and this increases stroke volume and therefore cardiac output

23
Q

what is starlings law of the heart

A

the energy of contraction is proportional to the initial length of the cardiac muscle fibre

24
Q

what three factors affect venous return/ central venous pressure

A

posture
muscle pump-constriction of veins by skeletal muscle
respiratory pump- inspiration creates an internal pressure difference . moves blood back to heart