14 capillary exchange Flashcards

1
Q

how does erythropoietin affect cardiac output

for low bp

A

increases the number of rbc which increases the volume of blood and increases venous return which fills ventricles more efficiently
increases cardiac output

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2
Q

describe the renin angiotensin system

for low bp

A

angiotensinogen is converted to angiotensin I by renin.

then converted to angiotensin II in the lungs by ACE

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3
Q

what can angiotensin II do

for low bp

A

bind to angiotensin I receptors and cause vasoconstriction

stimulates aldosterone secretion which increases blood volume as increased Na absorption so more water

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4
Q

describe the structure of capillaries for exchange

A

has thin walls for diffusion
slow blood flow to allow for exchange time
fenestrations for water to easily pass

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5
Q

what happens at the arteriole end of capillary

A

the delivery of water, oygen, glucose, ions amino acids to the bodys tissues

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6
Q

what happens at the venous end of capillary

A

the reabsorption water

removal of co2 waste molecules ion from the body cells into the venous end

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7
Q

what is capillary hydrostatic pressure

A

blood pressure

force on walls of capillaries, pushes water and solutes into interstitial fluid

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8
Q

what are osmotic forces

A

oppose capillary hydrostatic pressure

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9
Q

formula for net filtration pressure

A

net hydrostatic pressure - net colloid osmotic pressure

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10
Q

at the arteriole end what is the net hydrostatic pressure

A

thw capillary hydrostatic pressure (35mmHg arteriole to 18mmHg venous)
because there is no hydrostatic pressure in the interstitial fluid

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11
Q

at the arteriole end what is the net colloid osmotic pressure

A

the blood colloid osmotic pressure (25mmHg)

there is no interstitial fluid colloid pressure because theres few proteins inside (stays in blood)

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12
Q

at the arteriold end is the NFP + pr -

A

positive

the hydrostatic is greater than the osmotic

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13
Q

at venous end is the NFP + or -

A

negative

slower blood flow decreases the hydrostatic while osmotic stays tge same

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14
Q

why is NFP= closer towards the venous end

A

means grater distance across the capillary network is for net filtration, the delivery of materials to tissues
fast reabsorption at venous end

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15
Q

what will happen to blood pressure in a haemorrhage

A

the blood volume will decrease which will decrease the blood pressure and lower the capillary hydrostatic pressure. this lowers the net filtration pressure so there is greater fluid absorption
the volume of the interstitial fluid increases, increases circulation, plasma volume increases
recall of fluids increases blood pressure

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16
Q

how does the bbody protect against dehydration

A

plsma volume decreases due to water loss, the concentration of plasma porteins increases, which raises their osmotic potential. the blood colloid osmotic pressure increases for faster reabsorption and fluid recall

17
Q

high blood pressure

A

if capillary hydrostatic pressure Is too high or blood colloid osmotic pressure is too low this alters the blance of fluids and means there is net exit into peripheral tissue
fluid collects in extremities
systemic oedema

18
Q

is pulmonary arterial blood pressure higher or lower than systemic blood pressure

A

lower, as vascular resistance is very low

19
Q

describe what the pulmonary circulation does in low O2 and high O2

A

in low O2 pulmonary vessels constrict to shunt O2 to the alveoli cells
in high O2 the pulmonary vessels dilate and blood flow increases to absorb O2

20
Q

3 key characteristics of the brain

A

high blood flow rate for mass of tissue
blood flow is constant and preserved even in emergencies (cerebral vasodilation)
four arteries are used to supply brain and anastomoses inside the cranium

21
Q

key characteristics of the pulmonary circulation

A

coronary blood flow varies throughout thr cardiac cycle nd is influenced by heart rate
blood flow thorugh the coronary artery is interrupted during cardiac contraction as a result of compression

22
Q

how can we increase the pulmonary circulation to get more supply to the heart

A

vasodilator metabolites

adrenaline

23
Q

how is blood flow controlled in the skin

A

vasodilator metabolites
sensory stimulation by SNS
increase in body temp increases blood flow to skin by vasodilation