19. mechanics of breathing Flashcards

1
Q

what are two forces that provide resistance to breathing

A

lung compliance- the ease with which the lungs can be expanded
airway resistance

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2
Q

what affects compliance (3)

A

elasticity of lung tissue-connective tissue structure
mobility of chest wall/ thoracic cage
surface tension

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3
Q

does elastic recoil (returning to normal shape) of the lung aid or oppose inspiration

A

opposes inspiration, aids expiration

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4
Q

airway resistance

A

if the diameter of the bronchiole is affect, opposes both inspiration and expiration

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5
Q

formula for compliance

A

change in volume / change in pressure

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6
Q

what is surface tension caused by

A

intermolecular forces between molecules in a liquid

thin fluid layer between alveolar cells and the air is being stretched

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7
Q

what equation links pressure, surface tension and the radius of an alveolus together

A

P=2T/r

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8
Q

what is Laplaces law

A

at equilibrium the tendency of increased pressure to expand the alveolus balances the tendency of surface tension to collapse it

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9
Q

what is the function of pulmonary surfactant

A

reduces the surface tension increasing compliance

equalises the pressure differences between small sized and large sized alveoli so both can expand and contract easily

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10
Q

surfactant help to keep uniform alveolar size. it is more concentrated in ______ alveoli

A

smaller

lower surface tension means easier to inflate smaller alveoli

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11
Q

neonatal respiratory distress syndrome

A

lack of surfactant secretion in premature babies, which results in reduced compliance and alveoli collapse upon exhalation
it is also difficult to inflate the lungs

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12
Q

factors affecting airway resistance (2)

A

lung volume-bronchi dilate as lungs expand
bronchial smooth muscle
bronchoconstriction-parasympathetic nerves
bronchodilation-sympathetic nerves and adrenaline

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13
Q

what stimuli causes reflex bronchoconstriction

A

smoke dust irritants

histamine (allergic response)

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14
Q

how can we measure airway resistance

A

FEV1 / FVC x 100

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15
Q

what is FVC

A

forcibly breathing out vital capacity

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16
Q

what is FEV1

A

forced expiratory volume in one second

17
Q

breath sounds can tell us

A

the presence of mucus/fluid

if no breath sounds, collapsed lung?

18
Q

what does a peak flow meter do

A

measure the speed at which you breathe out

19
Q

how can we measure lung volumes and capacities

A

a spirometer

20
Q

what is the tidal volume TV

A

the volume of air inhaled or exhaled in one quiet breath

21
Q

residual volume RV

A

is the volume of air left in the lungs after a normal passive exhalation

22
Q

expiratory reserve volume ERV

A

the amount of air that can be forcibly exhaled after a normal tidal volume exhalation

23
Q

inspiratory reserve volume IRV

A

amount of air that can be forcibly inhaled after a normal tidal volume inhalation

24
Q

vital capacity VC

A

the maximum amount of air that can be expired after a maximum inspiratory effort
VC=TV + IRV + ERV

25
Q

inspiratory capacity IC

A

the maximum amount of air that can be inspired after a normal expiration
IC= TV + IRV

26
Q

functional residual capacity FRC

A

volume of air remaining in the lungs after a normal tidal expiration
FRC= RV + ERV

27
Q

total lung capacity TLC

A

maximum amount of air contained in lungs after a maximum inspiratory effort
TLC = TV + IRV + ERV + RV

28
Q

respiratory rate

A

the number of breaths per minute

29
Q

formula for pulmonary ventilation rate/ respiratory minute volume (amount of air moved per minute)

A

tidal volume x breathing frequency

30
Q

why does not all the tidal volume reach the alveolar exchange surfaces

A

anatomical dead space, there is volume of air in conducting passages that doesn’t participate in gas exchange

31
Q

what is the alveolar ventilation

A

the amount of air reaching alveoli each minute

respiratory rate x (TV - anatomical dead space)

32
Q

what can lead to having a larger lung volume

A
male 
taller 
athletes 
people living at high altitudes 
non smokers