contrast nephropathy

Question 1

n acetylcysteine indications

Answer 1

• paracetemol OD
• Prevent renal injury die to contrast
• respiratory secretions in hospital patients. this is in hospital. outsid ehospital carbocysteine is used

Question 2

MOA N-acetyl cysteine

Answer 2

in OD - replaces bodys glutathionew
.
- has antioxidant effect - which helps contrast nephropathy

• if in contact with mucus, breaks down dislphide bonds and reducing its viscosity. so can help sputum clearance

Question 3

SE N-acetyl cysteine

Answer 3

• anaphylaxis if in OD - but IGE independant, so can restart slower after reactions calms and given bronchodilator and antihistamine
• in mucolytic - given as nebs - bronchospasm. so give salbutomol before

Question 4

over how logn do u often give N-acetyl cystein for OD

Answer 4

21HRS, 3 doses.

Question 5

how to monitor N-acetylcysteine when given for OD

Answer 5

• inr, alt, creatinien conc at presentation, then completion