Contraction Physiology Flashcards
Transmembrane potential
Differences in the concentrations of ions on opposite sides of a cellular membrane.
Resting potential
The electrical potential of a neuron or other excitable cell relative to its surroundings when not stimulated or involved in passage of an impulse.
Depolarization
Loss of the difference in charge between the inside and outside of the plasma membrane of a muscle or nerve cell due to a change in permeability and migration of sodium ions to the interior.
Action potential
The change in electrical potential associated with the passage of an impulse along the membrane of a muscle cell or nerve cell.
Threshold potential
The action potential is an explosion of electrical activity that is created by a depolarizing current. This means that some event (a stimulus) causes the resting potential to move toward 0 mV. When the depolarization reaches about -55 mV a neuron will fire an action potential. This is the threshold.
Leak channels
Leak channels allow Na and K to move across the cell membrane down their gradients(from high concentration to low concentration).
Voltage gated ion channels
Are a class of transmembrane proteins that form ion channels that are activated by changes in the electrical membrane potential near the channel. The membrane potential alter the conformation of the channel proteins, regulating their opening and closing.
Neuromuscular junction
Is a chemical synapses between a motor neuron and a muscle fiber.
Motor neuron
A nerve cell forming part of a pathway along which impulses pass from the brain or spinal cord to a muscle or gland.
Acetylcholine (ACh)
A neurotransmitter that motor neuron release in order to activate a muscle. Parts of the body the use or are affected by ACh are cholinergic. Substances that inhibit ACh activities are called antichlinergics.
Acetycholinesterase (AChe)
The enzyme that breaks down ACh.
Axon terminal
Neurotransmitters are packaged into synaptic vesicles that cluster beneath the axon terminal membrane on the the persynaptic side of the synapse. The axon terminals release the neurotransmitters into the synapses.
Synaptic cleft
A gap between neurons or motor neurons and muscle cells.
Twitch
Single stimulus
Latent period
The delay between the receipt of stimulus by a sensory nerve and the response to it.