Contraception and Sterilization - Wootton Flashcards
Function of progesterone component in oral contraceptives
- Suppress LH and ovulation
- Thicken cervical mucous, inhibiting sperm migration
- Creating unfavorable atrophic endometirum
Function of estrogen component in oral contraceptives
- Improve cycle control by stabilizing endometrium and allowing less bleeding
Progestin-only oral contraceptives - fxn
Used by who?
Bad thing about it?
Making cervical mucous thick and impermeable
Breastfeeding women, or those w/ estrogen contraindication
MUST be taken w/in 2-3 hours of same time every day, or else must use backup for 2 days
Benefits of oral contraceptives
- Cycle regularity
- Less dysmenorrhea
- Less iron deficiency
- Less endometrial and ovarian cancer
Benign side effects of oral contraceptives
- Breakthrough bleeding (10-30%)
- Amenorrhea (1-5%)
- Bloating, weight gain, breast tenderness, nausea, fatigue, headache
Serious side effects of oral contraceptives
Venous thrombosis, PE, GB disease, stroke, MI, hepatic tumors
Transdermal patch - caution?
Side effects?
Not effective if > 198 lbs
Same, increased thrombosis risk (more than oral)
Vaginal ring - benefits
Better compliance, less breakthrough bleeding, can be removed for 3 hrs w/o losing efficacy
Groups that can’t use combo contraceptives
- Smokers > 35
- Personal Hx of thromboembolic event
- Hx of CAD, CVD, CHF, or migraine w/ aura
- DM, chronic HTN, SLE
- Moderate to severe liver disease (ex. hepatitis) or tumors
Depo – drug?
How to use?
MoAs
Medroxyprogesterone acetate
IM injection w/in first 5 days of menses, every 3 months
Thicken mucous, decidualize endometrium, block LH and ovulation
Benefit to Depo vs. patch
NOT affected by weight
Depo-provera – black box warning
Important in who?
Bone metabolism issue w/ decreased estrogen level
Adolescents
Side effects of Depo (3)
- Irregular bleeding (add back estrogen to help)
- Weight gain (HANGRY)
- Depression exacerbation (post-partum)
Indications of Depo vs. combo drugs (5)
- No estrogen (can use in contraindication)
- Want better compliance
- Women w/ seizures
- Sickle cell anemia
- Anemia 2º to menorrhagia
Contraindications to Depo (5)
- Pregnancy
- Unknown bleeding
- Breast malignancy
- Active or recent thrombophlebitis/thromboembolic event
- Liver dysfunction/disease
Nexplanon - what is it
Used for how long?
MoA?
Etonogestrel - rod implant
3 years
Thicken mucous, inhibit ovulation
Main side effect of rod implant
Irregularly irregular vaginal bleeding (no control of cycle)
Indications for rod implant
- Want a convenient method
- Breastfeeding
Contraindications for rod implant
SAME AS DEPO - pregnancy, thrombosis, liver disease, bleeding, breast cancer
Side effects of rod implant insertion
Infection, bruising, deep insertion, migration, persistent pain or paraesthesia at insertion site
3 IUDs in US (w/ durations)
Paragard (copper) - 10 years
Mirena (Levonorgestrel) - 5 years
Skyla (Levonorgestrel) - 3 years
Risks of IUDs
- Infection in first 20 days
- Ectopic pregnancy
- Uterine perforation at insertion
- Malposition
If IUD and pregnancy, do what?
Remove it (if string is visible)
Contraindications to IUD
- Breast cancer (Levonorgestrel ones)
- Recurrent puerperal sepsis
- Recent septic abortion
- Active cervical infection
- Wilson’s disease (copper one)
- Uterine malformations)
Benefits of IUD (4)
- Decreased menstrual bleeding
- Less dysmenorrhea
- Protection of endometrium in obesity (high estrogen)
- Convenient and long term
MoA of Copper IUD (Paragard)
- Interferes w/ sperm transport or fertilization and implantation
Only contraceptive method that protects from STIs
Condoms
Barrier methods are cheap, but ___
Have higher failure rate than others
Bad things about diaphragms (4)
- Must be used w/ spermicide
- Must be left in for 6-8 hours after intercourse
- Must be fitted and re-fitted
- More likely to get UTIs
Differences about cervical cap than diaphragm
- Fits cervix itself
- High risk of displacement and toxic shock syndrome
Sponge
Better in who
Bad things??
Small pillow w/ spermicide that fits on/over cervix
Nulliparous women
- Only one size
- Toxic shock risk if left in
What is Plan B?
For who?
Progestin only (Levonorgestrel) - 2 pills 12 hrs apart
OTC if older than 17
What is ella?
Ulipristal acetate
Male sterilization
How long to be effective?
Vasectomy - occlusion of vas deferens
10 weeks
Laparascopy - methods
Occlude fallopian tubes via... - Electrocautery - Clips - Bands Bands Salpingectomy (removal of tube)
Most common surgical procedure for sterilization
Mini-laparotomy
- Small infraumbilical or supraumbilical incision
Hysteroscopy - 2 approaches w/ this
- Transcervical tubal ligation
- Essure system
- Small coils in the fallopian tube, cause complete occlusion
Essure system - contraindications
Nickel or contrast allergies
Pelvic infection
Pregnancy
Essure system - benefits
Good for obese patients
Things w/ estrogen in it
Things w/ just progestin in it
Patch, ring, combo pills
IUD, Depo, progestin-only pills
26, G3P3, was using basal body temp system but wants a more reliable, less intensive method. Not ready for permanent sterilization. PHx of DVT. Does not smoke. What are her best options?
What if she was morbidly obese, did not want any more kids, and FHx of breast cancer?
IUD or Depo (NO ESTROGEN)
Essure
Biggest risk for patient w/ permanent sterilization
Regret