Contraception Flashcards
What percent of all pregnancies are unintended?
50%
Of the unintended pregnancies, what percent occur in couples who practice some form of birth control?
47%
What is the most common form of birth control used?
Oral BC pills
What is the MOA of spermicides?
Physical and chemical barrier to immobilize and kill sperm
What is the most common spermicide used?
Nonoxynol-9
What is the failure rate of spermicides used alone?
high
What percent of the population uses condoms regularly?
15%
What are the disadvantages of condom use?
Unreliable protection against HSV and HPV
What are diaphragms and what should they be used with?
Fitted by the healthcare provider, and should be used with a spermicide
How long does a diaphragm have to be left in for after coitus to be effective?
6-8 hours
Why is there an increased risk of UTIs with diaphragm use?
Mechanical obstruction of the outflow tract
What is the failure rate of diaphragms?
15% in most, 5% in perfect use
What are cervical caps?
Caps over the cervix that has to be fitted by a provider
What is periodic abstinence?
Rhythm method–Deciding when to abstain from intercourse based on calendar calculations
What is the pregnancy rates with periodic abstinence? Why?
20%– hard to tell exactly when ovulating, especially after pregnancy
What is coitus interruptus? What is the most common reasons for failure?
Withdrawal method—sperm in preejactulate may contribute to failure
What is the MOA of progestin in hormonal contraception?
Inhibits ovulation and increases thickening of the cervical mucus
What is the MOA of estrogen in hormonal contraception?
Maintain the endometrium and prevent unscheduled bleeding
What are the three general types of formulations for oral hormone contraceptives?
- Fixed dose combinations (E+P for 21 days)
- Combination phasic (2,3,4 different amount of E+P)
- Daily progestin
True or false: estrogen alone should never be used for contraception
True
What is Drospirenone?
Derived from 17-alpha spironolactone and resembles progesterone
What are the benefits of Drospirenone?
Anti-androgenic effects-blocks androgenic effects in the skin
What is the MOA of combination OC?
Prevent pregnancy by suppressing ovulation:progestational agent most effective
What is the MOA of Estrogen with BC pills? Progesterone?
Estrogen = Suppresses FSH secretion
Progesterone = suppresses LH, and inhibits ovulation.
Which increases cervical mucus thickness: progestin or estrogen
Progestin
What are the metabolic effects of hormonal contraception?
Estrogen component may cause n/v, breast TTP
-Weight gain by progestin
What is the effects on lipids of BC pills?
Insignificant difference in HDL and LDL cholesterol in low dose formulation
True or false: there are very small coagulation parameter changes with BC pills
True–unless there is an underlying procoagulation defect
What is the risk of having migraines with an aura, and BCP use?
Increases the risk of stroke