Constituents of Blood Flashcards

1
Q

what is the production of blood cells called and where does it take place?

A

haematopoiesis

in the bone marrow

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2
Q

what bones in an adult are able to produce RBCs?

A

the axial skeleton (skull, ribs, sternum, pelvis, proximal ends of femurs)

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3
Q

what are granulocytes?

A

white blood cells that contain granules

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4
Q

describe the appearance of eosinophils

A

bi-lobed

bright orange/red granules

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5
Q

describe the function of eosinophils

A

fight parasitic infections

involved in hypersensitivity reactions

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6
Q

describe the appearance of basophils

A

contain deep purple granules

nucleus often obscured

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7
Q

describe the function of basophils

A

mediates hypersensitivity reactions

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8
Q

what do the granules in basophils contain?

A

histamine

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9
Q

what do basophils bind to?

A

IgE

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10
Q

what is another name for neutrophils?

A

polymorphs

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11
Q

what are the three granulocytes?

A

basophils
eosinophils
neutrophils

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12
Q

describe the structure of neutrophils

A

segmented nucleus

neutral staining granules

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13
Q

how long do neutrophils last in circulation?

A

less than a day

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14
Q

describe the function of neutrophils

A

phagocytose invader cells

attract inflammatory cells

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15
Q

describe the structure of monocytes

A

large single nucleus

faintly staining granules, often vacuolated

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16
Q

describe the function of monocytes

A

circulate then enter tissues where they phagocytose cells

17
Q

which lives longer - neutrophils or monocytes?

A

monocytes

18
Q

what are monocytes called when they enter tissues?

A

macrophages

19
Q

describe the appearance of a mature lymphocyte

A

small
condensed nucleus
rim of cytoplasm

20
Q

describe the appearance of an activated lymphocyte

A

plentiful blue cytoplasm
large
more open nucleus