Connective Tissue (Exam 1) Flashcards

1
Q

CT is found everywhere except

A

The CNS

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2
Q

Characteristics of CT

A

relatively few cells
abundant Matrix
Contains very amounts of protein fibers

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3
Q

How is CT typically classified

A

Type of matrix, fiber density, and fiber organization

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4
Q

Functions of CT

A

physically supports other tissues
binds other tissues together
provides structural framework and opposes gravity
helps create body contours
Houses specialized tissues: Hematopoietic and lymphoid tissues

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5
Q

What is wharton’s jelly

A

embryonic CT in the umbilical cord

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6
Q

Name the types of adult CT

A

loose, dense, reticular, and elastic

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7
Q

Where is embryonic CT found

A

umbilical cord and in the pulp of developing teeth

composed of some collagen and elastic fibers but mostly an abundance of ECM

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8
Q

Loose adult CT

A

high ratio of fibroblasts to fibrous components
Type I collagen fibers and elastic fibers
Usually found beneath epithelial tissues of most organs, including the tunica adventitia of blood vessels
contains fibroblasts, mast cells, and macrophages, and capillaries

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9
Q

what type of collagen makes up loose adult CT

A

Type I collagen

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10
Q

Where is loose adult CT found

A

usually found beneath epithelial tissues of most organs, including the tunica adventitia of blood vessels

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11
Q

what is in loose CT

A

fibroblasts, mast cells, macrophages, and capillaries

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12
Q

Dense regular adult CT

A

high ratio of fibrous components to fibroblasts
thicker bundles of collagen than in loose CT
highly ordered bundles of collagen separated by single rows of fibroblasts
found in tendons and ligaments

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13
Q

Adult dense irregular CT

A

High ratio of fibrous components to fibroblasts
thicker bundles of collagen than in loose CT
Has no specific orientation of collagen bundles
found in fascia, submucosa of GI tract, and in dermis of integument

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14
Q

Reticular Adult CT

A

A type of dense irregular CT with a predominance of reticular fibers
associated primarily with the lymphatic tissue

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15
Q

which tissues is Reticular CT most primarily associated

A

The lymphatic tissue

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16
Q

Elastic CT

A

a type of dense irregular CT with an abundance of elastic fibers which form discontinuous lamellae
associated with walls of blood vessels

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17
Q

Where is elastic CT often found

A

in the walls of blood vessels

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18
Q

What cells produce the elastic fibers in the walls of blood vessels

A

Smooth muscle cells rather than fibroblasts

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19
Q

What are adipocytes derived form

A

undifferentiated mesenchymal cells and are distinguished by their unique appearance

20
Q

How large i the typical Adipocyte

A

150 micrometers

21
Q

what type of fat is unilocular

A

White fat

22
Q

what type of fat is multilocular

A

Brown fat

23
Q

What is meant by fat being multilocular

A

it is composed of numerous smaller lipid droplets

24
Q

Which of the tow types of fat cells has slightly more cytoplasm

A

Brown fat

25
Q

Which type of fat cells have abundant mitochondria

A

brown fat

26
Q

what ives brown fat the brown coloration

A

an abundance of mitochondria

27
Q

what are the two most common cells in CT Matrix

A

fibrocytes and fibroblasts

28
Q

what does the connective tissue matrix consist of

A

Protein fibers and ground substance

29
Q

What are the most abundant fibers of the connective tissue matrix

A

Collagen fibers

30
Q

what are the fiber types present in the connective tissue matrix

A

collagen (most common), reticular, and elastic fibers

31
Q

What is the ground substance of the cellular matrix composed of

A

Glycosaminoglycans and glycoproteins

32
Q

Location and function of Type I collagen fibers

A

General CT and bone

fxn Tensile strength

33
Q

Location and function of Type II collagen fibers

A

Hyaline and elastic cartilage

fxn: Tensile strength

34
Q

Location and function of Type III collagen fibers

A

Parenchyma of organs and walls of blood vessels

fxn: Reticular framework

35
Q

Location and function of Type V collagen fibers

A

Basal lamina

fxn: Meshwork, scaffolding, unknown

36
Q

Location and function of Type IV collagen fibers

A

Basement membranes

fxn: meshwork, scaffolding

37
Q

Location and function of Type VI collagen fibers

A

Ubiquitous

fxn: unknown

38
Q

Location and function of Type VII collagen fibers

A

Basement membrane of skin and amnion

fxn: anchoring fibers

39
Q

Location and function of Type VIII collagen fibers

A

Endothelium

fxn: unknown

40
Q

Location and function of Type IX-XII collagen fibers

A

Cartilage

fxn: unknown

41
Q

The cleaving of the non-helical terminal ends of pro-collagen converting it int tropocollagen occurs where

A

Immediately after secretion

42
Q

what are glycosaminoglycans (GAGs)

A

Large, negatively charged linear polymers (polysaccharides) consisting of repeated disaccharide units

43
Q

What is the charge of the ECM

A

negative

44
Q

along with _______ , GAGs form most of the amorphous substances of CT

A

Glycoproteins

45
Q

What are the 4 general groups tha GAGs fall into

A

Hyaluronic acid
Heparin and Heparin sulfate
Chondroitin sulfate and dermatan sulfate
Keratan sulfate

46
Q

Which GAGs are not covalently linked to protein to form proteoglycans

A

Hyaluronic acid