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Pediatrics > Connective Tissue And Joint Diseases > Flashcards

Connective Tissue And Joint Diseases Flashcards

1
Q

Which DMARD medication can cause proteinuria, leukopenia, thrombocytopenia and anemia

A

Gold salts

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2
Q

What joint is involved in RF- polyarticular JRA that is not involved in RF+ polyarticular JRA

A

The hip

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3
Q

What is deficient in Hemophilia A, B, C

A

Hemophilia A = Factor 8
Hemophilia B = Factor 9
Hemophilia C = Factor 11

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4
Q

What vascular disease is characterized by strawberry tongue, pharyngeal erythema, red chapped lips and high fever

A

Kawasaki disease (infantile polyarteritis)

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5
Q

Antibiotic treatment of Lyme disease in adults vs children

A 
Children = amoxicillin
Adults = doxycycline
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6
Q

Involvement of which joint in JRA indicates poor prognosis

A

The hip

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7
Q

According to ACR criteria, how old do you have to be to be diagnosis with JRA?

A

<16yo

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8
Q

What type of polymyositis/dermatomyositis is seen in children?

A

Type IV

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9
Q

Minor jones criteria

A

Fever, arthralgia, elevated ESR or CRP, prolonged PR interval

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10
Q

First and 2nd line therapy for JRA

A 
1st = NSAIDs
2nd = DMARDs
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11
Q

How many joints are involved in polyarticular JRA vs pauciarticular JRA

A 
Polyarticular = 5+ joints
Pauciarticular = < or equal to 4 joints
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12
Q

In hemophiliacs, what kind of exercises should be done when child has hemarthrosis?

A

Passive exercises to prevent joint stiffness and fibrosis

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13
Q

How often do patients with pauciarticular JRA need to see the ophthalmologist?

A

4x in the 1st year, then annually x 4 years

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14
Q

MC organism causing septic arthritis in neonates <2mths

A

Staphylococcus aureus

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15
Q

Which type of JRA can you see sacroiliitis?

A

Type II pauciarticular JRA

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16
Q

Etiology of rheumatic fever

A

Streptococcal infection

17
Q

3 things used to diagnose streptococcal infection

A
  1. Throat culture
  2. Rapid streptococcal antigen
  3. Elevated streptococcal antibody
18
Q

According to ACR criteria, how long do symptoms have to last to diagnose JRA?

A

> or = to 6 weeks

19
Q

Difference between type 1 and type 2 pauciarticular JRA

A

Type 1 = early onset (<4yo) in girls

Type 2 = late onset (9-10 yo) in boys

20
Q

Which type of JRA may be HLA-B27 positive?

A

Type II pauciarticular JRA

21
Q

Which type of JRA has risk of developing chronic iridocyclitis

A

Type I pauciarticular JRA

22
Q

Major Jones criteria

A 
Joints
Carditis
Nodules
Erythema marginatum
Sydenham Chorea
23
Q

MC organism causing septic arthritis in anyone >2yo, not sexually active

A

Staphylococcus aureus

24
Q

MC organism causing septic arthritis in sexually active adults

A

Neisseria gonorrhea

25
Q

MC type of JRA

A

Type 1 Pauciarticular JRA

26
Q

MC organism causing septic arthritis in RA patients

A

Staphylococcus aureus

27
Q

3 main clinical features of Lyme disease

A
  1. Heart disease (AV block)
  2. Arthritis/myalgias
  3. Neurological disease (bell’s palsy)
28
Q

MC organism causing septic arthritis in children between 2mth and 2 yo

A

Haemophilus influenzae

29
Q

Least common type of JRA

A

Still’s disease (systemic)

30
Q

What is the main side effect of Hydroxychloroquine?

A

Macular degeneration

31
Q

MC joint involved in pauciarticular JRA

A

The knee

32
Q

Which type of JRA has worst prognosis

A

RF+ polyarticular JRA

33
Q

Which type of JRA is HLA-DR4 positive

A

RF+ Polyarticular JRA

34
Q

Which type of JRA is at most risk of developing acute iridocyclitis

A

Type II pauciarticular JRA

35
Q

Diagnostic criteria for rheumatic fever

A

Presence of 2 major Jones criteria OR 1 major and 2 minor with evidence of streptococcal infection

36
Q

What is the hallmark sign of hemophilia

A

Hemarthrosis

Pediatrics (12 decks)

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