Connective tissue Flashcards
Tissue
A collection of cells to do a similar job
4 principle groups of tissues
Epithelial :
covers body-surface lines hollow organs body cavities ducts and forms glands
Connective tissue;
protects and supports body and organs binds organs together, stores energy reserves such as fat, helps provide body with immunity.
includes skeletal tissue cartilage and bone
Muscular tissue:
cells specialised for
contraction and generating force
Nervous system:
detects change in a variety of conditions responds by generating electrical signals e.g. action potentials
Functions of connective tissue
Bind together
Support
Strengthen other body tissues
Protect and insulate internal organs
Compartmentalise structures such as skeletal muscle
Major transport system e.g. blood
Store energy reserves – adipose
Main source of immune response
Components of connective tissue
1)Cells:
Chondroplasts:
immature cells — Produce extracellular matrix
Chondrocytes:
Mature cells — maintain extracellular matrix
2)Extracellular matrix:
Fibres- collagen (main protein),elastin,reticulin
Ground substance
Resident and fluctuating cells
Resident cells:
Fibroblasts-secret collagen active during wound repair forms granulated tissue
Lipocytes- store and synthesis fat
Fluctuating cells:
Macrophages- phagocytosis
Lymphocytes- phagocytosis
Mast cells- defence mechanism
Plasma cells- secret antibodies
Extracellular matrix
Fibres
Collagen
Secreted by fibroblasts flexible with high tensile strength orientation of fibres depends on stresses which act on tissue. Found in ligaments tendons and joint capsule
Elastin
Smaller and less numerous yellow and branched. Found in lungs skin arteries and veins
Reticular:
Form supporting structures of many glands and basement membrane of epithelial tissues supporting frame of many organisations
Extracellular matrix
Ground substance
Ground substance: Composed of water and large organic molecules gel like substance
- Complex combination of polysaccharides and proteins
- Polysaccharide – glycosaminoglycans
- Proteins – proteoglycans
Water molecules are trapped within the meshwork of these complexes producing viscous nature of gel
Acts as a mechanical barrier and means of diffusion of metabolites, electrolytes and gases between the tissues and capillaries
Epithelial tissue vs connective tissue
Epithelial tissue
- Little or no extracellular matrix
- Many cells tightly packed
- No blood vessels
- Form surface layer not covered by another tissue
Connective tissue
- Large amount of extracellular material
- Cells usually widely scattered
- Significant network of blood vessels not cartilage