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MSK! MSK! MSK! > Connective Tissue > Flashcards

Connective Tissue Flashcards

1
Q

What are the special types of CT?

A

Adipose, cartilage, bone, hematopoetic

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2
Q

What are the functions of connective tissues?

A
  • Structural framework of the body
  • Protection
  • Supports and interconnects other tissues
  • Energy storage
  • Transport fluids, cells, and dissolved chemicals throughout the body
  • Defense against invasion by microorganisms
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3
Q

What do fibroblasts do?

A

Produce collagens, proteoglycans, and glycoproteins

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4
Q

What do mesenchymal cells do?

A

They are the connective tissue stem cells

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5
Q

What do adipocytes do?

A

Store and release fats

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6
Q

What do chondrocytes do?

A

Produce and maintain cartilage components

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7
Q

What do osteoblasts do?

A

Produce bone compartments

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8
Q

What do hematopoietic stem cells do?

A

Produce red blood cells and immune cells

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9
Q

What is the most common type of collagen in the ECM?

A

Type 1

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10
Q

What is the stretchable fiber

A

Elastin

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11
Q

What do reticular fibers do?

A

Forms the supportive meshwork

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12
Q

What type of collagen is found in reticular fibers?

A

Type 3 collagen

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13
Q

What is a pathology that causes weak collagen fibers?

A

Scury and Ehlers-Danlos

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14
Q

What is a defect in elastin, more specifically fibrillin-1?

A

Marfan’s Syndrome

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15
Q

What are the principal targets of Marfan’s?

A

Ocular, skeletal, and cardiovascular

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16
Q

What are the cardiovascular anomalies with Marfan’s?

A

Dissecting aneurysms and mitral prolapse

17
Q

What is CD44?

A

Hyaluronate receptor

18
Q

What is the backbone to which the ECM connects?

A

Hyaluronan

19
Q

What is another name for embryonic connective tissue?

A

Warton’s jelly

20
Q

What is a low density tissue with both fixed and wandering cells?

A

Areolar

21
Q

What is fat containing tissue?

A

Adipose

22
Q

What is rich in reticular fibers and forms an open frame work to create a supportive mesh for holding free cells

A

Reticular

23
Q

What is characterized by fibers deposited in a random pattern? Where is it found?

A

Dense irregular CT, dermis of the skin

24
Q

What is characterized by fibers deposited in a highly regular pattern? Where is this found?

A

Dense regular CT, tendons connecting skeletal muscle to the bone

25
Q

What is rich in elastin fibers?

A

Elastic connective tissue

26
Q

What kind of connective tissue is found beneath membranous epithelia and around blood vessels, muscles, and nerves?

A

Loose connective tissue

27
Q

What functions to support and bind other tissues, hold body fluids, and defend against infection ?

A

Loose connective tissue

28
Q

What forms an open framework to create a labyrinth for holding free cells?

A

Reticular connective tissue

29
Q

Where is reticular connective tissue found?

A

Liver, bone marrow, lymph nodes, and spleen

30
Q

What has a tightly packed ECM and interwoven collagen fibers running in a random pattern?

A

Dense irregular connective tissue

31
Q

In what connective tissue are fibroblasts the principle cell type?

A

Dense irregular connective tissue

32
Q

Where is dense irregular connective tissue found?

A

Dermis of the skin, capsules that surround internal organs, perchondrium and periosteum, fascia

33
Q

Where is dense regular CT found?

A

Tendons, ligaments, apnoeuroses, dense fascia, joint capsules

34
Q

What is characterized by an ECM of tightly packed, regularly arranged collagen fibers?

A

Dense regular CT

35
Q

What has a wavy appearance when not under tension?

A

Dense regular CT

36
Q

What CT type is poorly vascularized?

A

Dense regular CT

37
Q

Where is elastic CT found? What does it contain?

A

Blood vessel walls, bronchiole tubes, and special ligaments (ligamentum nuchae); high proportion of elastic fibers

MSK! MSK! MSK! (15 decks)

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