Connective Tissue 1

Question 1

The function of connecting tissue….

Answer 1

Mechanical strength
General structure
Space filling
Physical and metabolic support

Question 2

Give three properties of connective tissue and explain them.

Answer 2

Elasticity- usually elastin, allow it to go back to its original form.
Tensile strength- Collagen, Resist pulling, streaching and tearing
Volume- usually made of large glycoprotein and carbohydrates, For the formation of ground substances

Question 3

Extracellular matrix is known as what?

Answer 3

Combination of matrix fibers and collagen

Question 4

Fibroblasts are derived from which fetal tissue?

Answer 4

Mesenchyme

Question 5

Specialised tissue for storage

Answer 5

Adipocytes

Question 6

packing and wrapping of material

Answer 6

Loose connective tissue

Question 7

Provide tough physical support

Answer 7

Dense connective tissue

Question 8

What are fibroblast and myofibroblast

Answer 8

Are both derived from mesenchyme

for synthesis, recycling, and maintenance of extracellular functioning.

Question 9

Describe the structure of fibroblast

Answer 9

Nuclei are condensed and elongated in a direction of a fiber
Cytoplasm barely visible
Cells are thin and long
Cytoplasm recesses extend to matrix

Question 10

What are myofibroblast

Answer 10

Myofibroblasts are activated forms of fibroblasts associated with contractile function and the role of repair. They have prominent nucleoli and the nuclei is large and cytoplasmic is extensive and basophilic. Basophilic extracellular matrix is prominent. They also secrete matrix.

Question 11

What are collagen

Answer 11

are found in most supporting tissue, Provide tensile strength, resist pulling, stretching, and tearing. They can form fiber, mesh/network some cell membrane material. There are 28 collagen, grouped according to their morphology, amino acid composition and physical property.

Question 12

Main structural collagen, Found in fibrous tissues. Stained pink using Haematoxylin and Eosin. Fibers vary in orientation, size and density and they use light microscopy.

Answer 12

Collagen 1

Question 13

Consists of fibrils of collagen in the ground substance. Found in hyaline cartilage.

Answer 13

Collagen II

Question 14

Often termed reticulin, prominent in highly cellular tissue, Forms a delicate branched reticular supporting meshwork.

Answer 14

Collagen III

Question 15

Found in the basement membrane. Forms mesh/network of collagen.

Answer 15

Collagen 4

Question 16

specialized anchoring fibrils which link basement membrane and extracellular matrix

Answer 16

Collagen VII

Question 17

Describe the elastin

Answer 17

Arranged in discontinuous sheet in the extracellular matrix. They are stretching and elastic recoil. Found in blood vessels, and lungs, they are important in blood vessels, and they are capable of bringing back the shape after the deformation of the structure. They have a different functions then they will be found in different proportions. Elastin fibre are eosinophils and bent light, they have special elastin stains.

Question 18

Amorphous, transparent semi-solid gel material. They have glycoproteins and complex carbohydrates and water-binding availability.

Answer 18

Ground substances.

Question 19

Differentiates the stain of ground substances in acian blue and H & E.

Answer 19

In alcian blue they are stained wispy blue in the background of pink stained collagen fibers and in H & E they are stained pale blue in the collagen.

Question 20

made up of type IV collagen and stained by PAS

Answer 20

Basement membrane

Question 21

functions of basement membrane

Answer 21

1. binding of epithelium tissue
2. Differentiation of epithelial and growth
3. Regulates permeability

Question 22

Sheet like arrangements of extra-cellular matrix proteins.

Act as an interface (in-between) between support tissues and epithelial/parenchymal tissues.

Answer 22

Basement membrane.

Question 23

Are adipose derived from mesenchyme true or false?

Answer 23

True

Question 24

what are adipose

Answer 24

are supportive tissue for the storage of adipocytes.

Question 25

differentiates two types of adipose tissue

Answer 25

White adipose tissue is pale yellow and they are , macroscopic. Brown adipose tissue are darker tint and appears brown.

Question 26

Chicken wire appearance

Answer 26

White adipose tissue

Question 27

Functions of white adipose tissue

Answer 27

forms part of shock-absorbing padding
Act as a thermal insulator under the skin
Storage and mobilization of triglyceride
Structural fill.

Question 28

function of brown adipose tissue

Answer 28

Regulation of temperature, and heat.

Question 29

What do the lobules of brown adipose tissue do?

Answer 29

Lobules are separated by fibrous septa which convey blood vessels and nerve fibers.

Question 30

Name the tissue that is found in the adrenal gland and is not found mainly in adults.

Answer 30

Brown adipose tissues

Question 31

Name two fixed (instrict) cells

Answer 31

1. Mast cells

2. Tissue fixed macrophages

Question 32

Wandering cells

Answer 32

all other white cells (leukocytes)

Question 33

Langerhans cells

Answer 33

dendritic skin of a cell

Question 34

Mast cell staining?

Answer 34

Toluidine blue

Question 35

Differentiate the location of nuclei on white adipose and brown adipose tissue

Answer 35

White- edge
Brown- centre