Concentrated Urine Flashcards
What is the system responsible for the formation of concentrated urine
countercurrent system
How does the kidney conserve water
By excreting concentrated urine
What are the basic requirements for forming a concentrated urine
High ADH
hyper osmotic Reno medullary interstitium
What is the function of ADH in concentrated your information
Increases permeability of distal tubule and collecting duct to water
What are the two forms of development and maintenance of hyperosmotic in Renal medullary interstitial
Countercurrents system
urea recycling
What are the two forms of countercurrent system
Countercurrent multiplier
countercurrent exchanger
Where does the countercurrent multiplier occur
Loop of Henle
What is the function of the countercurrent multiplier
Establishes the medullary osmotic gradient
What makes up the countercurrent exchanger
Vasa recta
What is the function of the countercurrent exchanger
Maintain gradients
What is the first step ( single effect) in countercurrent multiplication
Initial states of 300 in tube and interstitium
Sodium chloride reabsorbed from ascending limb
interstitial fluids now 400. Fruits in the a Ascending limb now 200
Equilibrium in a descending limb which becomes 400
What is stage 2 of countercurrent multiplication( flow of fluid)
Fluids with osmolarity of 300 enters distance in length
Hiigh osmolarity fluid of 400 in descending limb pushed down towards loop of Henley
What is the three of countercurrent multiplication (single effect again)
Sodium chloride reabsorbed out of the ascending limb and deposited in interstitial fluid
osmolarity increases even more at 500
osmolarity of fluid in ascending limb decreases further to 150
What is the floor in countercurrent multiplication (flow of fluid)
New fluid with osmolarity of 300 enter descending limb
High osmolarity fluid in descending limb pushed down to the loop of Henley
What is countercurrent exchange
 fluid of descending limb of vasa recta 300 osmolarity
Sodium chloride and urea defuses into descending limb and water diffuses out so that fluid in vasa recta can equilibrate with surrounding interstitial fluid
At bend of vasa recta osmolarity equal to interstitial fluid about 1200
At the ascending limb, interstitial fluid has decreased osmolarity so water diffuses in and solutes diffuse out for equilibration