Compounding Flashcards
what are the 4 categories of veterinary medications
1) drugs
2) biologics
3) pesticides
4) VHPs
biologics are regulated by:
a) VDD
b) veterinary drugs directorate
c) CFIA
d) pesticide mgmt regulatory agency
c) CFIA
VHP are regulated by:
a) VDD
b) veterinary drugs directorate
c) CFIA
d) pesticide mgmt regulatory agency
a
Drugs are regulated by:
a) VDD
b) veterinary drugs directorate
c) CFIA
d) pesticide mgmt regulatory agency
b
pesticides are regulated by:
a) VDD
b) veterinary drugs directorate
c) CFIA
d) pesticide mgmt regulatory agency
d
in order for a vet to dispense/prescribe medications there must be a valid
V-C-P-R
drugs are categorized based on (3)
safety concerns; abuse potential; ability of a lay person to understand and execute directions for their use
scheduling of drugs dictates (3)
how drug is ordered for dispensing; how drug is stored; how drug is obtained
NAPRA I drugs include (3)
narcotics (N); controlled drugs (C1-C3); targeted substances (TS)
T/F you need a prescription for NAPRA II drugs
F
NAPRA II drugs can be obtained with/without a pharmacist, and with/without a prescription
with; without
NAPRA III drugs can be obtained with/without a pharmacist, and with/without a prescription
without; without
what class of drugs can be obtained at retail stores
unscheduled
all NAPRA I drugs require
labelling
T/F you can prescribe refills for narcotics
F; need to label as dispense x pills every y days
whos responsibility is it to communicate with a client on medication use
the veterinarian
what is compounding
the combining of two or more ingredients, of which at least one is a drug or pharmacologically active component, to create a final drug in an appropriate dosage form
T/F splitting a tablet into two is an example of compounding
T
if you are giving a client a compounded drug, informed consent must include (3)
drug is not approved by the VDD of Health Canada; list of any potential ADRs; drug efficacy may be unknown and the drug is not rigorously tested
reporting ADRs from compounded products to the ADD of Health Canada is (voluntary/involuntary)
voluntary
why must you have a valid VCPR before prescribing compounded medications
to ensure that the response to therapy can be monitored
what is the biggest difference between compounded products and generic/brand-name products
generic/brand-names are HEALTH CANADA APPROVED
T/F generics are deemed bioequivalent to brand-name products
T
Generic/brand-name products are Health Canada approved. What 4 implications does this have
1) good manufacturing practices
2) subject to inspection
3) safety and efficacy data known
4) stability is known
T/F compounding pharmacies are not subject to inspection
F
what 4 signs are possible evidence of drug instability for liquid compounded drugs
1) colour change
2) cloudiness/film
3) precipitation
4) gas/odour
what 3 signs are possible evidence for drug instability in solid compounded products
1) crumbling
2) breaks/cracks
3) capsules/tablets sticking together
what are the 2 biggest causes of changes in drug stability
pH and temperature
compounded TD drugs need to be __________ to provide a dose in ____ to _____ volume
potent/soluble; 0.1-0.2 mL
what is a benefit of compounding to drug administration
it enhances patient/owner compliance (ex. flavouring agents)
what are 4 difficult products for a veterinarian to compound
1) sterile products
2) extended release products
3) transdermal products
4) opthalmic products
T/F with some exceptions, the importation of drugs for food animals is very restricted
T
T/F with some exceptions, the importation of drugs for companion animals is very restricted
F; loophole exists
what is the VDD EDR program
Emergency drug release program: permits veterinarians access to drugs not available in Canada to treat diseases on an emergency basis - vet must supply info like species, drug safety data, nature of emergency, amount of drug needed
