Composition and Structure of DNA Flashcards

1
Q

Nucleic acid

A

acidic substance made up of C,H,O,N,P

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2
Q

What are the 2 types of nucleic acid?

A

DNA, RNA

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3
Q

What does DNA stand for and where is it found?

A

Deoxyribonucleic acid, found in nucleus

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4
Q

What does RNA stand for and where is it found?

A

Ribonucleic acid, cytoplasm

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5
Q

What is DNA made up of?

A

Repeating units called nucleotides

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6
Q

What does each nucleotide in DNA have?

A

5-carbon sugar called deoxyribose, phosphate group, nitrogenous base

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7
Q

What are the kinds of nitrogenous bases? How many are there?

A

Four kinds, adenine, cytosine, guanine, and thymine.

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8
Q

What is a Purine nitrogenous base?

A

A double ringed one.

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9
Q

What are the Purine nitrogenous bases? How many are there?

A

2, Adenine and Guanine.

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10
Q

What is a Pyrimidine nitrogenous base?

A

A single ringed one.

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11
Q

What are the Pyrimidine nitrogenous bases? How many are there?

A

2, Cytosine and Thymine.

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12
Q

In the nitrogenous bases, what bonds to what?

A

Each Purine bonds to a Pyrimidine. Adenine and Thymine, and Guanine and Cytosine.

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13
Q

Who were James Watson and Francis Crick?

A

Scientists who worked for someone else. Using X-Ray photos of DNA, they formed a model of the structure of DNA.

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14
Q

What year were Watson and Crick?

A

1953

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15
Q

Who took the pictures Watson and Crick used?

A

Rosalind Franklin.

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16
Q

What did Watson and Crick determine?

A

DNA was in the shape of a double helix, phosphate and sugar formed the sides, nitrogenous bases the rungs, base pair bonds, complimentary.

17
Q

Double helix

A

Twisted ladder

18
Q

Why are the two strands of the double helix DNA complimentary?

A

Bc of the nitrogenous base pairings and bonds. If one was AGGTTAC, the other would read TCCAATG

19
Q

What is DNA replication?

A

Process of making a copy of DNA

20
Q

Template

A

pattern on which each new strand is built

21
Q

Why does each strand serve as a template?

A

In order to replicate itself, since each strand is complimentary.

22
Q

replication forks

A

areas where double helix separates (called this bc of their y shape)

23
Q

What is the first step of replication?

A

The double helix unwinds, and bases on one strand separate from the bases on the other.

24
Q

DNA polymerase

A

enzyme that attaches to each strand of the separated DNA during second step of DNA replication

25
Q

What does the DNA polymerase do?

A

moves along the strand, reads each base, attaching new complimentary bases according to the base pair rule

26
Q

When does replication stop?

A

When all of the DNA has been copied and the polymerases are signaled to detach, one per strand

27
Q

Conclusion of replication

A

2 DNA molecules are formed, each composed of a new strand and original strand (called semi conservative replication)

28
Q

In conclusion of replication, what do the sequences of bases in these two strands look like?

A

Identical to each other and the original DNA molecule

29
Q

What may happen during replication?

A

errors may occur and the wrong bases may be added

30
Q

What ability does DNA polymerase have that can prevent errors?

A

Proofread the new DNA strand, backtrack and removing the incorrect nucleotide, replace it w/ the correct one

31
Q

How many errors occur per nucleotides due to DNA polymerase?

A

1 error:1 billion nucleotides