COMPLEXATION Flashcards
Quantitative analysis of INORGANIC pharmaceutical products containing METAL IONS, such as; Al, Bi, Ca, Mg, & Zn.
COMPLEXATION METHOD
complexation method is performed using
GRAVIMETRIC METHOD
Time consuming: Precipitation, filtration, washing, and drying or ignition to constant weight.
GRAVIMETRIC METHOD
EDTA titration
VOLUMETRIC METHOD
EDTA MEANING
Disodium Ethylenediaminethetraacetate
When a METAL ION combine with a molecule which can donate electrons, the resulting compound is called a
COMPLEX
If the combining molecule contains TWO OR MORE GROUPS that donate electrons, this complex is called a
CHELATE
metals that yield weak or unstable complexes
MONOVALENT
_______will react with metal ions to form a water soluble, stable complex or chelate compound
EDTA
EDTA molecule which provides GROUPS FOR ATTACHMENT to metal ion is called
LIGAND
The term used to indicate the determination of a metal in the presence of another metal
MASKING
The metal ions which are determined by direct titration with EDTA
CA2+, Mg2+, and Zn2+
The INDIRECT method is applied to the analysis of Aluminum and Bismuth compounds
RESIDUAL TITRATION
Involve in a CHANGE IN VALENCE of the reacting substances
OXIDATION-REDUCTION METHOD
an indicator of choice in the titration with ceric salts
Ferrous phenanthroline ion (Ferroin)
