Comp Quiz #2

Question 1

__ inherited metabolic disorder; Elevation of serum phenylalanine causes severe mental disabilities and behavioral issues
Brain is primary organ affected by increased phenylalanine; dietary restrictions

Answer 1

Phenylketonuria

Question 2

__ inherited metabolic disorder; The absence or deficiency of hexosasamitninidase A. This produces an accumulation of gangliosides (GM2) within the brain; around 6 mo of age, child start to miss milestones

Answer 2

Tay-Sachs Disease (Lysosomal storage disorder)

Question 3

__ Inherited metabolic disorder: DNA mutation impairs functions of proteins. Muscle weakness, decreased coordination
Learning disabilities
Heart, kidney, liver disease
Respiratory, neurological, gastrointestinal disorders .

Answer 3

mitochondrial disorders

Question 4

__ Inherited metabolic disorder: Defect in the brain’s ability to metabolize copper; Kayser- Fleischer rings
Degenerative changes in the brain, hepatitis, cirrhosis of the liver
Athetoid or ataxic movements

Answer 4

Wilson’s Disease (hepatolenticular degeneration)

Question 5

Acid Base: Increase in bicarbonate (normal/ increased CO2)
Decreased H+
vomiting, muscle cramping, weakness, mental dullness

Answer 5

Metabolic alkalosis

Question 6

Acid Base Metabolic disorder
Decrease in bicarbonate (normal/ decreased CO2)
Increased H+
Renal failure, diarrhea, hyperventilation,

Answer 6

metabolic acidosis

Question 7

Bones become soft because of a calcium or phosphorus

deficiency

Answer 7

osteomalacia

Question 8

Decrease in bone mass secondary to bone reabsorption and decrease in osteoblast function

Answer 8

osteoporosis

Question 9

__ disease Increased osteoclastic activity, excessive bone formation with no structural integrity

Answer 9

paget’s disease

Question 10

Action: analgesia, pain relief, produce anti-inflammatory effects, and initiate anti-pyretic properties
Indications: mild-mod pain, fever, headache, muscle ache, inflammation (except acetaminophen), primary dysmenorrhea, reduction of risk of MI (aspirin only)

Answer 10

Nonopioid agents

Question 11

Action: analgesia for acute severe pain - medication stimulates opioid receptors within CNS to prevent pain impulses from reaching destination; some drugs may assist with dependency and withdrawal symptoms
Indications: mod-severe pain, induction of conscious sedation, management of opioid dependence, relief of severe/persistent cough (codeine)

Answer 11

opioid agents

Question 12

Action: Act on CNS to reduce skeletal muscle tone by depressing the internuncial neurons of the brainstem and spinal cord

Answer 12

muscle relaxants

Question 13

Action: provide hormonal, anti-inflammatory, or metabolic effects including suppression of articular and systemic diseases; reduce inflammation in chronic conditions that can damage healthy tissue through a series of reactions; vasoconstriction from stabilizing lysosomal membranes and enhancing effects of catecholamines.
Indications: replacement therapy for endocrine dysfunction, anti-inflammatory and immunosuppressive effects; treatment of rheumatic, respiratory, and various other disorders

Answer 13

Glucocorticoid Agents

Question 14

Action: slow or halt progression of rheumatic disease; act to induce remission by modifying pathology and inhibiting immune response responsible for rheumatic disease
Indications: rheumatic disease (preferably during early treatment)

Answer 14

Disease-Modifying Antirheumatic Agents (DMARDs)