Communicable diseases Flashcards
infectious vs communicable diseases
infectious- illness caused by specific microorganism
communicable- infectious disease transmitted from one person to another
endemic
diseases with relatively high but constant rates of infection in a particular population
epidemic
the number of new infections exceeds the normal number of infections in a population
pandemic
an epidemic that spreads across continents or worldwide
portal of exit
GI tract
reproductive system
resp tact
skin
modes of transmission
direct contact indirect contact food water borne airborne
HIV/AIDS
progressive deficency of immune cells, activation and immune response
via apoptosis, autoimmunity, direct killing of infected cells
transfer via blood and body fluids
its a single stranded envelope virus that lays dormant is host cell while it replicates and disseminates
ATTACKS- CD4, T helper, macrophages, dendritic
risk factors
high risk sexual behaviour, IV drug use, blood transfusion recipient, infants born with a HIV positive mother
SS of HIV
elevated viral load acute infection fever, malaise rash, oesophageal abrasions and lesions latency opportunistic infections
Chronic Vs Acute HIV infection
acute- rapid replication stage, extreme depletion of CD4 cells, B cells produce antibodies
chronic- powerful immune response, activation of virus within lymph noses
AIDs
is when CD4 cell numbers reach a critically low leven and CMI is complelety depleted
infections occur e.g pneumonia
most develop AIDs within 10 years depending on co-morbities, environment and health care access
supresses activity of bone marrow
tuberculosis
infection caused by aerobic bacterium (mycobacterium tuberculosis)
they have a unique cell wall structure which allows them to adapt
- lipid enhanced barrier
- carb structure that is facilitates its survival within macrophages
transmission via droplets
patho of tuberculosis
infectious droplets make their way into the airways
- gets caught in mucus and moved upwards for removal
- bacteria that bypasses this reach the alveoli and are engulfed by macrophages
ss of tuberculosis
cough >3 weeks fevers unexplained weight loss night sweats extreme lethargy loss of appetite blood stained sputum/cough
Chlamydia
caused by bacteria chlamydia trachomatis
transmitted by unprotected sex
treated by antibiotics
if left untreated can lead to PID and infertility
Gonorrhoea
caused by Neisseria gonorrhoeae
transmitted by sex or vaginal delivery
can lead to PID, ectopic pregnancy and infertility if not treated, treated with antibiotics
ss
dysuria, urethritis, purulent genital discharge, often assymptomatic